SLPCohortJournal of autism and developmental disorders2026

Quality of Life and Societal Cost in Autistic Children: An Exploratory Comparative Study Pre- and Post-Diagnosis.

Leontine W Ten Hoopen, Pieter F A de Nijs, Kirstin Greaves-Lord and 3 others

PMID 40057931

WHAT IT FOUND

Autistic children's total annual health-related costs and quality-of-life scores did not change significantly after diagnosis, although usual-activity problems, behavioural scores, general practitioner, physiotherapy and hospital outpatient costs fell.

Key findings

01Total annual health-related costs were lower after diagnosis than before, but the change was not statistically significant.

02Caregiver-reported health-related quality of life increased slightly after diagnosis, but the increase was not statistically significant.

03Some specific healthcare costs changed significantly: general practitioner, physiotherapy and hospital outpatient clinic costs decreased, while psychologist or psychiatrist practice care increased.

STILL TO COME

How it was doneWhat they foundWhat it means for SLPs

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What it does not show

Only 36 of 134 children had both pre- and post-diagnosis reports, so the analysed group was small and may not represent the referred children. Caregivers reported service use and quality of life by proxy, and autistic children often rate their own quality of life higher than caregivers. The study did not collect caregiver informal care or productivity loss, so total societal costs were incomplete. It did not record which interventions were delivered between pre- and post-diagnosis, so changes cannot be attributed to diagnosis or therapy. The sample was Dutch, clinically referred, and mostly well-functioning, so it may not apply to children in the general population or other health systems. Small sample and exploratory analysis mean non-significant total cost and quality-of-life changes could be due to low power. Ageing over the interval may explain changes because age could not be stratified.

Declared interests

The paper names SSWO as the funder. The supplied text does not include an author conflict-of-interest disclosure.

The easy way to misread this

Do not conclude that an autism diagnosis caused lower total costs or better quality of life. The total cost and quality-of-life changes were not statistically significant, and the study did not control for interventions, ageing, or other changes over time.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →