Prognostic models for identifying adults with intellectual disabilities and mealtime support needs who are at greatest risk of respiratory infection and emergency hospitalisation.
C M Perez, A P Wagner, S L Ball and 4 others
PMID 28497469WHAT IT FOUND
Adults with intellectual disabilities who need mealtime support and had prior respiratory infection, epilepsy or caregiver-reported swallowing problems were linked to respiratory infection.
Increasing mealtime support needs and epilepsy were linked to emergency hospitalisation for eating and drinking problems.
Key findings
01In the linear-age model, epilepsy (odds ratio 6.46, P = 0.014) and a history of respiratory infection in the first year (odds ratio 10.59, P = 0.002) were the only significant predictors of respiratory infection in the second year.
02In the linear-age model for emergency hospitalisation for eating and drinking problems, increasing mealtime support needs (odds ratio 7.41, P = 0.039) and epilepsy (odds ratio 6.30, P = 0.022) were significant predictors.
03In the stepwise respiratory-infection model, caregiver-reported swallowing problems were significant (odds ratio 4.66, P = 0.012), while diagnosed dysphagia was not retained.
STILL TO COME
How it was doneWhat they foundWhat it means for OTsWhat it means for SLPs
Read the rest of this summary
You get three full summaries a month, free, and we do not ask for a card. Search, the TL;DRs and your library stay unlimited either way.
What it does not show
These are exploratory prognostic models, not validated risk scores. The authors could not split the data into training and validation samples because the sample was small. Only 142 of 726 invited people agreed to take part, and only 127 were used in the models, so selection bias may limit generalisability. Some information was recalled for the year before the baseline interview, so recall bias may affect variables such as prior respiratory infections. Missing data reduced the respiratory-infection model to 119 people and the hospitalisation model to 124 people. The age term was modelled in a quadratic form, and the authors state it cannot be interpreted strictly as an age effect. Epilepsy severity and other details were not collected, so the study cannot say whether epilepsy control or severity explains the associations.
Declared interests
None declared. The research was commissioned by the National Institute for Health Research under its Research for Patient Benefit programme, grant reference PB-PG-0906-11098. Some authors were supported by the NIHR Collaboration for Leadership in Applied Health Research and Care East of England, and one author was supported by the Medical Research Council, Unit Programme number U105292687.
The easy way to misread this
Do not use these models as validated risk scores. The authors did not validate them because the sample was small, and only 142 of 726 invited people agreed to take part, so selection bias may affect the results.