Predictors of mortality and ICU requirement in hospitalized COVID-19 patients with diabetes: A multicentre study.
Md Asaduzzaman, Mohammad Romel Bhuia, Mohammad Zabed Jillul Bari and 4 others
PMID 36575597WHAT IT FOUND
In hospitalized COVID-19 patients with diabetes, lower oxygen saturation on admission, older age, and higher neutrophil count were linked with death.
These are monitoring and escalation cues, not a standalone prediction.
Key findings
01Diabetes was reported as associated with higher in-hospital death risk (2.3 times, p = 0.02).
02Among patients with diabetes, adjusted death risk was higher with older age and higher neutrophil count, and lower with higher platelet count or higher admission oxygen saturation.
03Among patients with diabetes, adjusted ICU requirement was associated with age, ischemic heart disease, white blood cell count, D-dimer, and admission oxygen saturation.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The study is retrospective and used hospital records, so it cannot prove that any factor caused death or ICU need. It included only hospitalized patients, so it does not describe people with milder illness managed outside hospital. Pre-hospital glucose control, diabetes duration, HbA1c, diabetes complications, BMI, and prescribed treatments were not available or not analysed. The crude death and ICU differences between patients with and without diabetes did not reach statistical significance, even though adjusted models reported associations. The predictors were selected by a stepwise process, so the final list may not be stable. The study was done in four hospitals in one region of Bangladesh, so the findings may not transfer to other populations.
Declared interests
No external funding was received, and the authors declared no conflict of interest.
The easy way to misread this
Do not read this as a validated bedside score or as proof that diabetes causes death. The study is retrospective, several key diabetes and treatment variables were missing, and the crude comparison of death rates between patients with and without diabetes was not statistically significant.