Applied Evidence

Patient-reported voice and swallowing outcomes and their impact on quality of life in the late postoperative period following total thyroidectomy.

CoDAS · 2026 · Cohort · SLP

Lívia Lima do Nascimento Silva, Vivian Lisboa de Lucena, Ana Flávia de Sales Cândido and 3 others

PMID 42561306

Women 6+ months after total thyroidectomy still report significant voice and swallowing symptoms, with fatigue and mental health the most affected quality-of-life areas.

Voice symptoms dominate over swallowing. These patients may need ongoing SLP assessment well past the typical recovery window.

Key findings

1Vocal symptoms contributed the largest proportion (48.98%) to the total TVSQ score, predominating over swallowing and cervical-thoracic symptoms.

2The median total TVSQ score was 26 on a 0-to-80 scale, with the two highest individual scores (49 and 48) belonging to participants who also had neck dissection.

3Among quality-of-life domains, fatigue scored highest, followed by emotional aspects, anxiety, cognitive problems, and depression.

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What it does not show

Only 17 participants, all biological females, from a single hospital — results cannot be generalised to men, to other surgical contexts, or to other populations. No instrumental voice or swallowing tests were performed; findings rest entirely on self-report questionnaires. Descriptive statistics only; no inferential analysis, no comparison group, and no control for confounders. Time since surgery ranged widely (2004–2022), and surgical techniques and care protocols changed over that period, introducing a confounding factor the authors acknowledge. Possible selection bias: patients were recruited from the hospital's own SLP department records and from those attending appointments, which may over-represent symptomatic individuals. The TVSQ Brazilian-Portuguese version does not yet have defined clinical cutoffs, so scores cannot be interpreted against established thresholds.

Declared interests

No financial support or conflicts of interest declared.

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