OTSystematic ReviewOccupational therapy international2026

Outcome Measures of Fatigue in Adults With Cancer Receiving Radiation Therapy: A Scoping Review.

Courtney Apostol, Danielle Hitch

PMID 42226073

WHAT IT FOUND

Most fatigue scales used in radiation therapy clinics barely ask about daily activities or roles.

Occupational therapists should pair whatever fatigue tool they use with their own occupation-focused assessment, since no single scale captures how fatigue affects a patient's daily life.

Key findings

01Only six of the 13 fatigue measures identified included items about daily activities, social participation, or role performance, leaving most tools poorly aligned with what occupational therapists need to assess.

02No single fatigue measure fully covers the physical, emotional, cognitive, and spiritual dimensions of cancer-related fatigue as defined by the NCCN, and none comprehensively addresses occupational therapy's focus on functional outcomes.

03The authors recommend that occupational therapists combine fatigue-specific tools with occupation-focused assessment and observation to get a complete picture of how fatigue affects a patient's daily life.

STILL TO COME

How it was doneWhat they foundWhat it means for OTs

Read the rest of this summary

You get three full summaries a month, free, and we do not ask for a card. Search, the TL;DRs and your library stay unlimited either way.

Already have one?

What it does not show

Most included studies came from high-income Western countries, and breast, head and neck, and prostate cancers made up 83% of the sample—findings may not transfer to other cancer types or healthcare settings. No formal quality appraisal was performed, so the rigour of the 12 included studies was not evaluated. Only English-language publications were included and grey literature was excluded, potentially missing emerging tools or non-English validation work. No eligible studies published after 2022 met the criteria, so the evidence base may be dated. The review adopts an occupational therapy lens (activity and participation), which may not reflect the primary purpose of most fatigue measures, which are designed to assess symptom severity rather than functional impact.

Declared interests

The authors declare no conflicts of interest. Open-access publishing was facilitated by Deakin University through a Wiley–Deakin University agreement via the Council of Australasian University Librarians.

The easy way to misread this

Do not read the finding that 6 of 13 measures include participation items as evidence that those tools are adequate for occupational therapy assessment. The review explicitly states that no measure fully aligns with the NCCN definition of cancer-related fatigue or comprehensively addresses occupational therapy's focus on functional outcomes, and the authors recommend supplementing any fatigue scale with occupation-focused assessment.

Read it on PubMed →