Order of Onset of Physical Frailty and Cognitive Impairment and Risk of Repeated Falls in Community-Dwelling Older Adults.
Mei-Ling Ge, Nadia M Chu, Eleanor M Simonsick and 2 others
PMID 36852758WHAT IT FOUND
Older adults who developed cognitive impairment and physical frailty within a year had the highest repeated-fall risk, 28.3%.
Frailty-first versus cognitive-impairment-first did not differ after adjustment. This is an association, not a tested prevention programme.
Key findings
01Repeated falls in the year after new frailty or cognitive impairment were most common when both conditions appeared together (28.3%), compared with 20.3% for frailty first and 12.7% for cognitive impairment first.
02After further adjustment for obesity, comorbidities and mobility disability, co-occurrence had an odds ratio of 2.35 for repeated falls versus cognitive impairment first, and 1.62 versus frailty first.
03Frailty first versus cognitive impairment first was not a statistically significant difference for repeated falls after adjustment (odds ratio 1.45, P=0.070).
STILL TO COME
How it was doneWhat they foundWhat it means for PTsWhat it means for RNs
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What it does not show
This was an observational study, so it cannot show that frailty or cognitive impairment caused the falls, only that they occurred together. Falls were measured by asking about the past 12 months, and the study did not record how many falls occurred, so frequent minor falls may have been missed. The analysis looked only at the year after new frailty or cognitive impairment, so longer-term fall risk was not assessed. 328 people were excluded because fall information was missing; they were older and had more disease burden, so the analysed sample may not represent all older adults. Some people excluded because of death or drop-out were sicker than those analysed, which may make the observed associations conservative. The authors note that the co-occurrence pattern may be linked to dementia, but they did not establish that dementia caused the falls.
Declared interests
The authors declared no conflicts of interest. The paper lists NIH and non-U.S. government research support.
The easy way to misread this
Do not read the higher repeated-fall rate in the co-occurrence group as proof that treating frailty or cognitive impairment prevents falls. This study did not test an intervention, and the frailty-first versus cognitive-impairment-first difference did not reach statistical significance after adjustment.