SLPOtherMolecular autism2018

Operationalizing atypical gaze in toddlers with autism spectrum disorders: a cohesion-based approach.

Quan Wang, Daniel J Campbell, Suzanne L Macari and 2 others

PMID 29651331

WHAT IT FOUND

Toddlers with autism looked less like typical toddlers on a research gaze measure during face-to-face speech and sandwich making, but not moving toys.

Within autism, gaze clustered most on toys and sandwich making and least on speech.

Key findings

01On the gaze measure, toddlers with autism looked less like typical toddlers during sandwich making and face-to-face speech, but not during moving toys.

02Within the autism group, gaze was most similar among autism toddlers during moving toys and sandwich making, and least similar during face-to-face speech.

03Lower gaze typicality scores in the autism group during sandwich making and face-to-face speech were associated with higher social-affect symptom scores; no such association appeared for moving toys or repetitive-behavior scores.

STILL TO COME

How it was doneWhat they foundWhat it means for SLPs

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What it does not show

The method was tested on only one 3-minute video, so it may not generalize to other stimuli or settings. The Joint Attention condition was excluded from the main model because the typical group had no high-cohesion frames in that condition. The correlations with autism symptoms were exploratory and not corrected for multiple comparisons. The same 10% high-cohesion cutoff was used for all groups, but it corresponded to different screen distances or visual angles in the autism and developmental-delay groups. The study included toddlers only, so it is unclear whether the method applies across ages. The study measured gaze during one eye-tracking session and did not test treatment or outcomes, so it cannot tell therapists whether changing gaze behavior helps. Some diagnoses were made later than the eye-tracking visit, though the authors state diagnosis stability is high.

Declared interests

The study was funded by the National Institute of Mental Health, the National Center for Advancing Translational Sciences, the Eunice Kennedy Shriver National Institute of Child Health and Human Development, the Division of Behavioral and Cognitive Sciences, the Congressionally Directed Medical Research Programs, and Autism Speaks. The supplied text does not state author conflicts of interest.

The easy way to misread this

Do not use this gaze score to diagnose autism or to track therapy progress. The study tested one video in toddlers, excluded the joint-attention condition from the main model, and the symptom correlations were exploratory.

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