Novel gait training alters functional brain connectivity during walking in chronic stroke patients: a randomized controlled pilot trial.

Only nine participants in each group completed the study. Participants were ambulatory people with chronic stroke who could walk independently for at least 6 m, so results may not extend to acute stroke or more severe motor deficits. Both groups also received ambulation training, so the contribution of each component cannot be separated. The neurophysiological assessment was done during regular treadmill walking, which may have been more familiar to the regular treadmill group than the turning treadmill group. The study used 32 EEG channels and one muscle signal, so it cannot fully describe brain network spatial patterns. The supplied text does not identify a single primary outcome, and it reports multiple connectivity comparisons. The paper says follow-up gait maintenance is known from previous work, but brain network changes at follow-up were not measured.

The supplied metadata lists non-U.S. government research support, but the article text does not include a funding statement or author conflict declaration.

Do not conclude that turning treadmill training alone caused the brain and gait changes. Participants also received ambulation training, and the study cannot separate the contribution of each component. Only nine participants in each group completed this pilot.