Nonsurgical Treatment Options for Muscle Contractures in Individuals With Neurologic Disorders: A Systematic Review With Meta-Analysis.
Christian Svane, Jens Bo Nielsen, Jakob Lorentzen
PMID 33778477WHAT IT FOUND
Nonsurgical treatments for muscle contractures in neurologic disorders showed no convincing benefit.
Stretch and robot-assisted therapy improved range of motion by only 3 and 1 degrees, below the 5-degree threshold for clinical importance. Botulinum toxin, electrical stimulation, and physical activity showed no significant effects.
Key findings
01The review found no convincing evidence supporting the use of any nonsurgical treatment option for muscle contractures.
02Stretch interventions produced a pooled short-term effect of 3 degrees on passive range of motion, which is below the 5-degree threshold considered clinically important.
03There was a significant lack of objective measures in the included trials, with only 18 of 70 trials using tools like passive stiffness or torque-controlled goniometry.
STILL TO COME
How it was doneWhat they foundWhat it means for PTsWhat it means for OTs
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What it does not show
Most included trials did not use objective measures of muscle contractures, relying instead on standard goniometry which can be influenced by the rater. Many trials did not blind the assessor, introducing a high risk of bias. The review combined data from different joints (e.g., ankle, elbow) using absolute PROM measures, which may not be directly comparable across joints. The severity of contractures at baseline varied across studies and could not be quantified or controlled for in the analysis. Past treatment history of participants was largely unknown and could have influenced the results. Two authors of the review were also authors of included trials, though they did not extract data from those specific studies. The review focused on short-term effects (up to 1 week post-intervention), so long-term outcomes remain unclear.
Declared interests
The authors declared no conflicts of interest. The study did not require ethical approval as it was a review of published trials.
The easy way to misread this
Do not interpret the statistically significant 3-degree improvement from stretching as a clinically meaningful gain. The authors explicitly state that an effect of less than 5 degrees is not considered clinically important, and the quality of evidence is limited by the lack of objective measurement in most trials.