SLPCohortMolecular autism2021

Non-verbal IQ and change in restricted and repetitive behavior throughout childhood in autism: a longitudinal study using the Autism Diagnostic Interview-Revised.

V Courchesne, R Bedford, A Pickles and 12 others

PMID 34391468

WHAT IT FOUND

In autistic children followed from diagnosis to age 11, the overall presence of restricted and repetitive behaviors decreased, but some specific behaviors increased.

Change also depended on non-verbal IQ.

Key findings

01Across the whole sample, the presence of restricted and repetitive behaviors decreased over time.

02The age-related change was not uniform: Unusual Sensory Interest, Repetitive Use of Objects, Other Complex Mannerisms and Unusual Preoccupations decreased with age, while Circumscribed Interests and Sensitivity to Noise increased. Unusual Attachment to Objects also decreased when a less strict correction was used.

03Non-verbal IQ had no overall effect on behavior presence, but it interacted with age for Difficulties with Change in Routine, where the behavior increased over time in children with lower non-verbal IQ.

STILL TO COME

How it was doneWhat they foundWhat it means for SLPs

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What it does not show

The study used parent-reported ADI-R answers, so a behavior could have been present but not reported, or reported differently at different ages. The analysis looked only at whether each behavior was present or absent, not how often it occurred or how severe it was. Fewer children were assessed at age 11 than at diagnosis, so later childhood patterns depend on which families stayed in the study. Only 28 girls were included, and sex was not analysed, so the findings may not apply equally to autistic girls. Non-verbal IQ was estimated from one WISC-IV index at age 8, and conventional IQ testing may underestimate ability in autistic children, especially those with limited speech. The study was observational and did not assign or test any therapy, so it cannot show that a treatment caused behavior change. Some item-level findings appeared only with less strict multiple-comparison corrections, so they are less certain than the strictly corrected findings. The paper did not analyse adaptive abilities or other developmental indicators alongside age and IQ.

Declared interests

The supplied text does not include an author conflicts-of-interest statement. The article metadata labels the work as supported by non-U.S. government research.

The easy way to misread this

Do not read the age-related decreases or increases as evidence that therapy caused them. This was an observational study of parent-reported behavior, and no treatment was assigned or tested.

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