PTOTPilotJournal of neuroengineering and rehabilitation2025

Noisy galvanic vestibular stimulation and static balance in parkinson's disease: a multimodal resting‑state fMRI feasibility study.

Yun Su Hwang, Jihwan Min, Yongseon Yoo and 5 others

PMID 41402826

WHAT IT FOUND

In 41 patients with Parkinson's, one session of noisy galvanic vestibular stimulation improved Berg Balance scores immediately and at one week.

Functional reach and discomfort also improved, but Timed Up and Go did not change significantly at first. No sham group was used.

Key findings

01Berg Balance Test scores improved significantly from 47.22 to 49.05 immediately after stimulation and remained significantly above baseline at one week.

02Timed Up and Go performance showed no significant immediate improvement, with scores changing from 15.44 to 15.15 seconds.

03The study had no sham control, so observed changes cannot be definitively attributed to the stimulation rather than practice effects or expectation.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

There was no sham-controlled comparison group, so it is impossible to know if the improvements were due to the stimulation itself or to practice effects and patient expectation. The study was a feasibility pilot with a small sample size (41 patients) and did not have prospective power justification. Multiple outcomes were analyzed without pre-specified multiplicity control, meaning some significant findings (like FRT and TUG overall time effects) did not survive stricter statistical corrections. Stimulation and scanning were not performed concurrently, so the study characterizes post-stimulation effects rather than real-time neural responses.

Declared interests

The study was funded by the Ministry of Science and ICT, South Korea, and the Korea Health Industry Development Institute. No commercial conflicts of interest were declared by the authors.

The easy way to misread this

Do not assume the improvements in balance were caused by the electrical noise itself. Because there was no sham group, the gains in Berg Balance and Functional Reach could be due to the patients practicing the tests or expecting to improve.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →