Nanocomposites used in the treatment of skin lesions: a scoping review.
Wevernilson Francisco de Deus, Camylla Layanny Soares Lima, Ana Luiza Barbosa Negreiros and 3 others
PMID 38743957WHAT IT FOUND
Nanocomposite dressings were mapped across 21 studies in burns, pressure injuries, venous ulcers and diabetic foot ulcers, with reported healing outcomes.
The review did not judge study quality or show benefit over standard care, so it should not change wound care.
Key findings
01The review included 21 studies of nanocomposite coverings for skin lesions, including burns, pressure injuries, venous ulcers and diabetic foot ulcers.
02The review did not assess the quality of the included studies, and no study compared the isolated effect of components carried by the nanocomposites.
03Silver nanocomposites were the most common type studied, and the review says silver use should be limited to no more than four weeks.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The search may have missed eligible studies that were not indexed in the databases or gray literature sources. The reviewers did not assess the quality of the included studies. The included studies were small and varied widely in wound type, nanocomposite design, comparison treatment and outcome, so they cannot support one practical recommendation. No included study compared the isolated effect of the components carried by the nanocomposites, so any benefit cannot be separated from other treatments. The review says there are insufficient human studies, especially phase III trials, to support applying nanomaterials in practice.
Declared interests
The supplied text states financial support from CAPES, Brazil, with Funding Code 001; no other funding or conflict declaration appears in the supplied text.
The easy way to misread this
Do not read this as proof that nanocomposite dressings heal wounds better than standard care. The review did not assess study quality, many included studies were small or case reports, and no study separated the nanocomposite from other treatments given at the same time.