SLPOtherTrends in hearing2016

Modeling the Effects of Sensorineural Hearing Loss on Sound Localization in the Median Plane.

Robert Baumgartner, Piotr Majdak, Bernhard Laback

PMID 27659486

WHAT IT FOUND

Outer hair cell damage in a model of hearing predicted poorer up-down and front-back sound localization.

Errors increased as damage became more severe, and complete damage predicted near chance accuracy.

Key findings

01Predicted localization errors increased as outer hair cell gain decreased, and complete outer hair cell damage yielded performance close to chance.

02Medium-spontaneous-rate fibers predicted the best localization performance, and low-spontaneous-rate fibers predicted the worst.

03The model's predicted sensitivity to 10 dB level changes was strongly related to its predicted localization performance.

STILL TO COME

How it was doneWhat they found

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What it does not show

The study tested a computer model, not people with hearing loss, so it does not show how any patient will localize sounds. The model was calibrated using data from normal-hearing listeners, and the hearing-loss conditions were simulated rather than measured. The simulations assumed the auditory system had fully adapted to the hearing loss, which may not happen in a real patient. The work tested only quiet listening with broadband noise, so it does not address speech understanding or noisy environments. The auditory nerve fiber categories were simplified, and the model was not fitted directly to human auditory nerve responses. For strong spectral modifications, the model tended to overestimate local error. The paper reports no tested treatment, so it cannot support a therapy recommendation.

The easy way to misread this

Do not read the model's predicted localization deficits as evidence that a tested treatment can improve localization. The paper reports model simulations, not a clinical intervention study.

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