RNOtherJournal of nursing care quality2026

Infusion Pump Interoperability and Resulting Alert Reduction: Multisystem Findings.

Jeannine W C Blake

PMID 41928352

WHAT IT FOUND

After interoperability, drug library alignment, functional testing, and quarterly data analytics service, 22 infusion pump sites had fewer programming alerts, edits, overrides, and potential averted overdose events.

Alerts fell from 73.4 to 48.6 per 1000 events, but patient outcomes and workload were not measured.

Key findings

01Alerts at interoperable sites fell from 73.4 to 48.6 per 1000 programming events, a 33.8% decrease (P < .001), after interoperability, drug library alignment, functional testing, and quarterly data analytics service.

02Edits fell from 18.9 to 8.7 per 1000 programs, overrides from 54.7 to 39.7, and potential averted high-risk overdose events from 4.4 to 2.5, all with significant decreases.

03Drug library compliance changed from 98.5% to 99.5%, and potential averted underdose events from 0.4 to 0.5 per 1000 programs; neither change was significant.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

This was a retrospective analysis of existing pump logs, and the authors state the comparison cannot establish causality. The control system also received the quarterly data analytics service and showed non-significant decreases in alerts and overrides. Staff changes and drug library revisions during the observation windows were not controlled. The analysis could not link scanning compliance to alert outcomes. It only counted errors caught by the dose error reduction system; errors that did not trigger an alert were not captured. It did not measure patient outcomes, adverse events, nurse workload, or alert fatigue. Drug library compliance was already very high at most sites, so there was little room to show improvement. One site's large compliance rise was due to switching from Plum A+ to Plum 360, not interoperability alone.

Declared interests

The dataset was initially gathered for product development and quality improvement initiatives between the hospitals and ICU Medical, Inc. The study was supported by ICU Medical, Inc. Dr Blake is an advisor and consultant for ICU Medical, Inc.

The easy way to misread this

Do not read the alert reduction as proof that interoperability alone improved patient outcomes or reduced nurse workload. The sites also received drug library alignment, functional testing, and quarterly data analytics service, and the study did not measure patient adverse events, workload, or alert fatigue.

Read it on PubMed →