PTRCTNeurorehabilitation and neural repair2026

Higher Intensity Walking Training in Individuals With Chronic Motor Incomplete Spinal Cord Injury: A Randomized Clinical Trial.

T George Hornby, Abbey Plawecki, Jennifer Lotter and 6 others

PMID 41454653

WHAT IT FOUND

Fastest overground walking speed did not show a clear advantage for higher-intensity training, but peak treadmill speed and 6-minute walk distance were greater with higher intensity in chronic motor incomplete spinal cord injury.

Key findings

01The primary fastest overground walking speed favored higher-intensity training, but the between-group difference was not statistically significant after correction.

02Peak treadmill speed during graded exercise testing improved significantly more with higher-intensity training, with a post-training mean difference of 0.25 m/s.

03The secondary 6-minute walk test distance improved more with higher-intensity training, with mean differences of 40 m at post-training and 48 m at follow-up.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

The study was done at one site, so the results may not apply everywhere. The sample was modest, with 53 participants randomized. Fourteen participants did not attend the 3-month follow-up because they lived out of state. The primary peak treadmill speed outcome was not blinded because staff monitored ECGs during testing. The primary fastest overground speed result was not statistically significant after correction. Many participants did not maintain the assigned heart-rate targets: 12 of 28 in the high-intensity group averaged below 70% heart-rate reserve, and 9 of 25 in the low-intensity group averaged above 40% heart-rate reserve. Four high-intensity participants could not reach above 50% heart-rate reserve and had very slow baseline self-selected speeds below 0.20 m/s. Five participants could not complete baseline metabolic testing at the slowest treadmill speed. The study enrolled only ambulatory individuals more than 6 months after injury, so it does not address people who cannot walk or those soon after injury.

Declared interests

The article reports a conflict of interest: TGH is co-owner and CEH is partially employed by the Institute for Knowledge Translation.

The easy way to misread this

Do not conclude that higher-intensity walking training clearly improves fastest overground walking speed. The fastest speed difference favored higher intensity but was not statistically significant after correction, and the significant peak treadmill speed result was not blinded.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →