PTRCTJournal of neuroengineering and rehabilitation2025

High-intensity interval training with robot-assisted gait therapy vs. treadmill gait therapy in chronic stroke: a randomized controlled trial.

Jiae Kim, Jungwha Do, Cho Rong Bae and 3 others

PMID 40753404

WHAT IT FOUND

Robot-assisted gait training with high-intensity intervals improved walking speed more than treadmill walking alone in 44 people with chronic stroke.

The robot group gained 0.14 m/s versus 0.01 m/s, but the design cannot separate the robot from the interval training.

Key findings

01The primary outcome (10-meter walk test) improved significantly only in the robot group, with a between-group difference of 0.14 m/s versus 0.01 m/s (p < 0.001, d = 1.2).

02Both groups improved on the Functional Ambulation Category, Berg Balance Scale, and Fugl-Meyer lower-extremity score, but the robot group showed significantly greater gains on all three.

03The study design does not allow the specific contributions of the robot and the high-intensity interval protocol to be separated from each other.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

The control group received active treadmill gait therapy, so the study cannot tell you whether the robot, the high-intensity interval structure, or the combination produced the gains. Twenty-two patients per group at a single hospital in South Korea; the authors call the study exploratory and note that randomisation may not have fully eliminated baseline imbalances (the robot group started with a lower Fugl-Meyer lower-extremity score). All participants were in the chronic phase (more than 6 months post-stroke) and walked with assistance or supervision, so the result does not extend to acute or subacute patients or to those who are already walking independently. Assessors were not blinded, and subjective measures such as the Berg Balance Scale and Fugl-Meyer score may have been influenced by knowing which group the patient was in. The high-intensity protocol was the same for everyone; no comparison was made between different interval structures or intensities.

Declared interests

Funded by the National Rehabilitation Center, Ministry of Health and Welfare, Korea. No industry sponsorship or author conflicts of interest are declared in the text provided.

The easy way to misread this

Do not read this as proof that robot-assisted gait therapy specifically improves walking speed in chronic stroke. The control group also received active treadmill training, and the authors state plainly that the design cannot separate the robot from the interval protocol. With 22 patients per group at one site and no blinding of the assessors, the result is a hypothesis to test in a larger trial, not a settled practice change.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →