PTOTRNCohortNursing & health sciences2025

Frailty, Nutrition, and Quality of Life in Urban-Dwelling Older Adults Facing Vulnerability: Observational Study in Primary Heath Care Settings in Underpopulated Areas.

Kalyne Patrícia de Macêdo Rocha, Larissa Amorim Almeida, Nathaly da Luz Andrade and 11 others

PMID 40974270

WHAT IT FOUND

Poor functional independence and performance were the strongest indicators of vulnerability in older adults in Brazilian primary care, and poor nutrition was also linked.

Quality of life was linked to vulnerability but was not analyzed as a predictor.

Key findings

01Functional independence and performance were the strongest frailty domains linked to vulnerability, with lower function associated with odds up to 3.96 times higher.

02Poorer global nutritional status was associated with vulnerability, but its predictive value was lower and less consistent than frailty.

03Quality of life was linked to vulnerability, especially physical role functioning, but was not included in the regression model.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for RNs

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What it does not show

Participants were recruited by convenience from two low-population municipalities in Brazil, so the sample may not represent older adults elsewhere. The study looked at one point in time, so it cannot show that frailty or poor nutrition caused vulnerability. People with severe cognitive impairment or non-oral feeding were excluded, so findings may not apply to those patients. Quality-of-life measures were too closely related for the regression model, so their independent role is unclear. Some data were self-reported, and participants may have withheld information they found embarrassing.

Declared interests

The authors declared no conflicts of interest. Funding was from Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico, and the Brazilian Federal Agency for Support and Evaluation of Graduate Education (CAPES).

The easy way to misread this

Do not read these results as proof that exercise, nutrition support, or screening changes vulnerability. The study was cross-sectional and measured associations at one time, so it cannot show cause or effect.

Read it on PubMed →