OTSurveyJournal of autism and developmental disorders2024

Finding Similarities in Differences Between Autistic Adults: Two Replicated Subgroups.

Tulsi A Radhoe, Joost A Agelink van Rentergem, Carolien Torenvliet and 3 others

PMID 37438586

WHAT IT FOUND

Autistic adults formed two replicated subgroups: one had higher social skills and positive affect, the other lower sense of control, more worries and negative affect.

The low-control subgroup had more psychological difficulties and lower quality of life.

Key findings

01In the replication sample, the high-grip autism subgroup had N=124 (47%) and showed higher scores on social skills, attention switching, communication, and positive affect, while the low-grip subgroup had N=130 (50%) and showed the lowest sense of mastery and the highest negative affect.

02In the replication sample, the low-grip subgroup reported more cognitive difficulties, more psychological difficulties, and lower quality of life than the high-grip subgroup.

03The main replicated autism subgroups did not differ in education, age, sex, or IQ.

STILL TO COME

How it was doneWhat they foundWhat it means for OTs

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What it does not show

The study used cross-sectional self-report data, so it cannot show whether the subgroups stay the same over time or predict future outcomes. The analysis excluded adults with intellectual disability, adults under 30, and people with insufficient Dutch, so it does not apply to all autistic adults. Most autistic adults were diagnosed after age 18 (94% in the original data and 97% in the replication data), so findings may not generalize to adults diagnosed in childhood. Only adults with average to high intelligence were included, and the sample was mostly White and highly educated; race/ethnicity and socioeconomic status were not assessed. The third autism subgroup had only seven adults in the replication data and was treated as an artifact rather than a valid subgroup. ADHD adults were split between the autism and comparison subgroups, so it is unclear how specific the autism subgrouping is to autism. Missing data led to exclusion of 12% of the original sample and 6% of the replication sample. The grouping method used score patterns rather than cut-off scores, so the labels should not be read as simple severity levels.

Declared interests

The study was funded by Nederlandse Organisatie voor Wetenschappelijk Onderzoek. Four older/autistic adults were paid for think tank contributions. The supplied text does not include a full author conflict-of-interest declaration.

The easy way to misread this

Do not read the high-grip and low-grip labels as fixed types or proof that either group needs more therapy. The groups came from cross-sectional self-report patterns, and the study did not test interventions or follow people over time.

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