Factors associated with COVID-19 death in pregnant women hospitalized in Intensive Care Units.
Milena Ricioli Ribeiro, Marcela de Andrade Pereira Silva, Leticia Furlan de Lima Prates and 3 others
PMID 39194128WHAT IT FOUND
Unvaccinated pregnant women with COVID-19 in Brazilian ICUs had 2.72 times higher chance of death.
Dyspnea, obesity, chronic cardiovascular disease and non-white race were also associated with higher chance.
Key findings
01During March 2020 to March 2022, 3,547 pregnant women with COVID-19 were reported in Brazilian ICUs, and 811 died (22.8%).
02In the final model, unvaccinated women had 2.72 times higher chance of death, and women with dyspnea had 1.73 times higher chance.
03In the final model, obesity, chronic cardiovascular disease and non-white race were associated with higher chance of death (1.51, 1.65 and 1.29 times).
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
Read the rest of this summary
You get three full summaries a month, free, and we do not ask for a card. Search, the TL;DRs and your library stay unlimited either way.
What it does not show
The study used secondary surveillance data, which can have underreporting and data entry errors. It only included pregnant women already hospitalized in ICUs, so it does not describe risk among all pregnant women with COVID-19. Cases recorded as both pregnant and postpartum were excluded because the records could not separate them. Missing data were excluded for specific variables, which may affect some comparisons. Because this was an observational record study, it can show associations, not proof that vaccination, obesity, cardiovascular disease, race or symptoms caused death.
The easy way to misread this
Do not read the 2.72 times higher chance of death in unvaccinated women as proof that vaccination alone caused the difference. This was an observational study of ICU records, and it cannot separate vaccination from other differences between vaccinated and unvaccinated women.