Evaluation of Intervention Fidelity in a Multisite Clinical Trial in Persons With Multiple Sclerosis.

The paper reports fidelity monitoring and process data, not efficacy outcomes. The trial was ongoing, so clinical results were not presented. Participants had to have computer and Internet access outside classes, and computer experience varied widely. No pre/post intervention knowledge testing was included, so direct assessment of participants' receipt of content was limited. Exercise completion data may overstate effective practice because several participants repeated exercises instead of progressing. Multiple cohorts at the same site made contamination possible, and participants were asked not to share study details. Goal attainment progress was reported only for participants with 3- and 6-month data.

The authors report no conflicts of interest. Lumos Labs, Inc., the manufacturer of the online computer training program, provided weekly reports documenting participants' exercise completion.

Do not read this as evidence that computer-assisted cognitive rehabilitation improves cognition in multiple sclerosis. The paper reports fidelity monitoring and dose data, not clinical outcomes.