Estimates of the Prevalence of Speech and Motor Speech Disorders in Youth With 22q11.2 Deletion Syndrome.
Adriane L Baylis, Lawrence D Shriberg
PMID 30515510WHAT IT FOUND
Most children and adolescents with 22q11.2 deletion syndrome were classified with a motor speech disorder: 82.4% of 17.
Dysarthria was most common. Motor speech disorder rates were similar in comparison groups.
Key findings
01Of the 17 analysed participants with 22q, 82.4% met criteria for a motor speech disorder.
02Childhood dysarthria, alone or with childhood apraxia of speech, was the most prevalent motor speech disorder, affecting 7 (41.2%) of the 17 participants.
03The motor speech disorder prevalence estimates were not different from the Down syndrome, fragile X syndrome, or galactosemia comparison groups in the statistical tests used.
STILL TO COME
How it was doneWhat they foundWhat it means for SLPs
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What it does not show
The analysed group was very small, and the authors describe the findings as initial prevalence estimates. Families may have self-selected because of speech concerns, so children with more severe speech problems could be overrepresented. The sample was limited to English-speaking participants with 22q and no permanent bilateral hearing loss, so it may not apply to other language or hearing profiles. Many participants had already had velopharyngeal dysfunction surgery, so the study cannot show what speech or motor speech status was before treatment or estimate presurgical severity. Group cells were too small to test associations between motor speech classifications and hearing, swallowing, motor, cognitive, language, therapy, or velopharyngeal dysfunction variables. The primary velopharyngeal dysfunction rater knew diagnosis and surgical status, although not the motor speech classifications.
Declared interests
The research was supported by the National Institute on Deafness and Other Communication Disorders grant R01 DC000496. The supplied text does not report commercial funding or author conflicts of interest.
The easy way to misread this
Do not treat the motor speech disorder prevalence as definitive or as evidence that 22q11.2 deletion syndrome causes motor speech disorders. The sample was small and self-referred, and the authors describe the findings as initial estimates.