Epidemiology of Alzheimer Disease and Related Dementia Among Medicare and Medicaid Enrolled Autistic Adults, 2011-2019.
Salina Tewolde, Samuel B Rosenberg, Josue Antonio G Estrada and 4 others
PMID 40166852WHAT IT FOUND
Dementia was common in autistic adults aged 30 and older covered by Medicaid or Medicare, rising from 2.09% in 2011 to 8.11% in 2019.
Mean age at first dementia claim was 59.3 years.
Key findings
01Among 90,229 autistic adults, 8,267 had Alzheimer disease and related dementias, representing 9.2% of the cohort.
02Dementia prevalence rose from 2.09% in 2011 to 8.11% in 2019, and from 16.5% to 29.3% among adults 75 or older.
03Mean age at dementia onset was 59.3 years, and after accounting for other factors the dementia-free curves did not meaningfully differ by sex.
STILL TO COME
How it was doneWhat they foundWhat it means for SLPs
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What it does not show
The dementia and autism diagnoses came from billed claims codes, not from clinical tests, imaging, or record review. There was no comparison group of adults without autism or intellectual and developmental disabilities, so the study cannot show that autism itself raises dementia risk. Only adults with Medicaid or Medicare claims for autism were included, so autistic adults without those claims and privately insured autistic adults are not represented. More frequent healthcare contact in Medicaid and Medicare enrollees may increase the chance that dementia is recorded. The rise in prevalence over time may reflect better identification, longer survival, or changing risk rather than a true increase in dementia. Sex was recorded only as male or female, and ethnicity options were limited, so gender and cultural differences may be missed. The study reported counts by dementia type, but did not test clinical outcomes or treatment effects.
Declared interests
The article lists NIH extramural research support. No additional funding or conflict-of-interest declaration is given in the supplied text.
The easy way to misread this
Do not conclude that autism causes dementia or that this proves a higher risk than the general population. The study used billed claims, had no non-autistic comparison group, and cannot separate diagnosis from healthcare contact.