RNRCTAdvances in skin & wound care2025

Efficacy of Stamp Skin Grafting to Promote the Healing Process of Chronic Wounds.

Huilin He, Li Zhu, Xiaohong Chen and 5 others

PMID 40626721

WHAT IT FOUND

Stamp skin grafting combined with wet dressings reduced chronic wound healing time from 39.2 to 30.3 days and dressing costs from 803 to 411 RMB compared to wet dressings alone.

Pain relief improved after the first change. Graft survival averaged 95.3%.

Key findings

01Healing time was significantly shorter in the skin-grafting group (30.3 ± 8.9 days) compared to the control group (39.2 ± 9.8 days), despite the grafting group having larger initial wound areas.

02Dressing change costs were significantly lower in the skin-grafting group (411 ± 59 RMB) than in the control group (803 ± 201 RMB).

03The survival rate of tiny skin grafts at the second dressing change was 95.3% ± 7.9%, with 69.0% of patients achieving a 100% survival rate.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The skin-grafting group had significantly larger wound areas at baseline than the control group, which complicates direct comparison of healing time and costs. The study did not assess pretreatment scar conditions, which may bias healing effect evaluations. Posttreatment scar formation was assessed only by visual inspection without patient self-reporting. The study was conducted at a single center.

The easy way to misread this

Do not interpret the reduced healing time and costs as solely due to the grafting technique without considering that the grafting group had larger wounds at baseline. The benefit might be related to the specific wound types or sizes included, and the lack of blinding could influence subjective pain assessments.

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