Effects of Transcranial Direct Current Stimulation Followed by Treadmill Training on Dual-Task Walking and Cortical Activity in Chronic Stroke: A Double-Blinded Randomized Controlled Trial.
Pei-Ling Wong, Yea-Ru Yang, Shih-Fong Huang and 1 others
PMID 36943024WHAT IT FOUND
Cathodal tDCS, a brain-stimulation current, before treadmill training improved cognitive dual-task walking more than sham tDCS plus treadmill training in 45 people with chronic stroke.
It did not help motor dual-task walking.
Key findings
01Cathodal tDCS plus treadmill training improved cognitive dual-task walking speed and cadence more than sham tDCS plus treadmill training.
02Cathodal tDCS plus treadmill training improved lower-limb motor control more than sham tDCS plus treadmill training.
03Motor dual-task walking performance did not differ between groups.
STILL TO COME
How it was doneWhat they foundWhat it means for PTs
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What it does not show
The study included only people who could walk at least 10 m without walking aids and had Mini-Mental State Examination scores of 24 or higher, so it does not show what happens in patients with more severe walking or cognitive impairment. Outcomes were measured only before and after the 12 sessions, so it is unknown whether the gains lasted. Brain activity was measured only in the contralesional hemisphere, not the lesional hemisphere, so the study does not explain interactions between both hemispheres. The study tested tDCS before treadmill training only; it does not show whether tDCS given at the same time as or after treadmill training has the same effect. Each group had only 15 participants, and the paper does not report how many participants had missing post-test data or dropped out.
Declared interests
The authors declared no conflicts of interest.
The easy way to misread this
Do not conclude that cathodal tDCS alone improves walking. All groups received treadmill training, and the advantage was for cathodal tDCS added before treadmill training. The study also did not measure follow-up, so it does not show whether gains last.