PTPilotJournal of neuroengineering and rehabilitation2026

Effects of robotic assistance on muscle activation and fatigue during overground walking in non-disabled individuals: an exploratory study.

Margaux Simon, Joris Boulo, Laurent J Bouyer and 1 others

PMID 41832593

WHAT IT FOUND

Walking with the exoskeleton changed muscle patterns more than changing assistance level did.

Lower assistance did not simply reduce muscle activation. The first full-assistance trial felt mentally harder than later trials.

Key findings

01Hamstring activation differed between the first 100% trial and both the 40% trial and the second 100% trial, but not between the 40% and second 100% trials.

02The EMG median-frequency measure did not differ across trials in the medial gastrocnemius, and the hamstring median-frequency change was accompanied by lower hamstring muscle activity.

03Overall perceived workload and mental demand were highest in the first 100% trial and lower in the 40% trial and the second 100% trial.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

The study was done in 15 non-disabled young adults, and the paper says the results are applicable only to individuals without disabilities until data in people with CNS lesions are available. The sample was small, and the paper says this limits firm conclusions about the lack of difference when returning from lower assistance to full assistance. The trial order was fixed: 100%, then 40%, then 100%. The first full-assistance trial differed from later trials, so early exposure to the device may explain more of the change than the assistance level itself. The intended reduction from 100% to 40% assistance may not have translated into an actual 60% change in what participants felt, because power can be lost at the exoskeleton-user interface. Instructions differed between the 100% and 40% trials, which could confound the comparison, although the authors note the pattern did not match the expected instruction effect. Baseline walking without the exoskeleton was done at a comfortable speed, not at the slower exoskeleton speed, so a same-speed natural walking comparison was not available. Only 100% and 40% assistance were tested, and levels below 40% were described as very challenging to control.

Declared interests

The funding sentence names only the Faculty of Medicine, Universite Laval.

The easy way to misread this

Do not conclude that lower assistance reduces muscle activation compared with full assistance. The clearest differences were between the first full-assistance trial and later trials, not between lower assistance and the second full-assistance trial, and the study was done in non-disabled walkers.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →