Applied Evidence

Effects of cassava wax immersion on pain, pressure pain threshold, and upper extremity function among patients with trigger finger.

Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao · 2026 · RCT · PT

Narongsak Khamnon, Vitsarut Buttagat, Sittiporn Punyanitya and 3 others

PMID 42688482

Ultrasound plus cassava wax immersion produced significantly greater pain relief than ultrasound alone in trigger finger, though both groups improved on all measures.

Small single-centre trial (38 patients, 4 weeks) — promising but not definitive.

Key findings

1Both groups showed significant pain reduction from baseline, but the experimental group (ultrasound + cassava wax) had significantly greater pain reduction than the control group (ultrasound alone) at every post-treatment time point.

2The experimental group showed significantly greater increases in pressure pain threshold than the control group at the immediate and short-term time points, while the control group's PPT improved significantly only at the short-term point.

3Both groups reduced the frequency of finger-locking episodes, but no significant between-group difference was found for this outcome.

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What it does not show

Only 38 participants (19 per group) at a single site in northern Thailand, limiting generalisability and statistical power for smaller effects. Follow-up was 1 month after a 4-week intervention; whether the added benefit of the wax bath persists beyond that is unknown. Single-blind design: patients knew whether they received the wax bath, which could bias self-reported outcomes such as VAS and DASH. The MCID thresholds used (VAS ≥ 2, DASH ≥ 10–15) are not specific to trigger finger, so the 'clinically meaningful' claim rests on borrowed cut-offs. The DASH items were re-grouped into five domains by the authors rather than using a validated subscale structure, so domain-level interpretation is tentative.

Declared interests

No conflicts of interest declared. The study was funded by Mae Fah Luang University, the institution where it was conducted.

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The study

Participants
38 (19 per group); 74 initially screened, 36 excluded
Certainty of evidence
Moderate

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Cite

Narongsak Khamnon, Vitsarut Buttagat, Sittiporn Punyanitya, et al. Effects of cassava wax immersion on pain, pressure pain threshold, and upper extremity function among patients with trigger finger. Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liao. 2026.

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