Effects of 12-week circuit exercise program on obesity index, appetite regulating hormones, and insulin resistance in middle-aged obese females.
Seol-Jung Kang, Jong-Hyu Kim, Zhao Gang and 4 others
PMID 29410591WHAT IT FOUND
Over 12 weeks, obese women who did circuit exercise, with diet instructions for all, had lower weight, body fat, insulin, and insulin resistance; satiety hormone leptin fell and hunger hormone ghrelin rose.
The control group did not exercise and worsened on several blood measures.
Key findings
01Weight decreased in the exercise group, and the exercise and control groups changed differently over time.
02Leptin decreased and ghrelin increased in the exercise group, and the control group moved in the opposite direction.
03Insulin and the insulin resistance index decreased in the exercise group, and the control group increased on both.
STILL TO COME
How it was doneWhat they foundWhat it means for PTs
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What it does not show
Only 26 women were studied, all from one health promotion center in South Korea, so the results may not apply to other groups. The paper does not describe how randomisation was done, whether participants or assessors were blinded, or whether a primary outcome was pre-specified. All participants were instructed to record and voluntarily reduce food intake, and dietary habits were not completely controlled, so the effect of circuit exercise alone cannot be separated. Daily physical activity was not analyzed, so differences in usual activity between groups are unknown. Fasting glucose did not significantly decrease in the exercise group. No follow-up beyond 12 weeks is reported.
The easy way to misread this
Do not conclude that circuit exercise alone caused the weight, hormone, and insulin changes. All participants also recorded food intake and were instructed to voluntarily reduce consumption, and the study did not fully control diet.