Effect of an Oral Nutrition Supplement Containing Collagen Peptides on Stratum Corneum Hydration and Skin Elasticity in Hospitalized Older Adults: A Multicenter Open-label Randomized Controlled Study.
Tatsuya Nomoto, Shinji Iizaka
PMID 32195722WHAT IT FOUND
Hospitalized older adults taking a daily oral nutrition supplement containing collagen peptides, vitamins, and minerals for 8 weeks had higher forearm skin hydration and elasticity than controls.
It did not test prevention of skin tears or pressure injuries.
Key findings
01Mean stratum corneum hydration rose from 43.7 at baseline to 51.7 at week 8 in the group given the supplement containing collagen peptides, vitamins, and minerals, while control values were 41.3 at baseline and 41.4 at week 8.
02Mean skin elasticity rose from 0.67 at baseline to 0.74 at week 8 in the group given the supplement containing collagen peptides, vitamins, and minerals, while control values were 0.64 at baseline and 0.66 at week 8.
03No adverse effects or events were reported, and no skin problems such as skin tears were reported.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
The trial was open-label, so participants knew whether they received the supplement. The supplement contained collagen peptides, vitamins, and minerals, and meals were modified, so the effect of any single component cannot be isolated. The study required 44 participants to detect the planned difference, but 39 were analyzed after three participants were removed from each group. It did not test prevention of skin tears or other skin problems; no participant developed a skin tear, and skin tears were not the primary outcome. Participants had to be able to eat 80% of meals and had to have no forearm skin treatment or special skin care routine, so results may not apply to patients who did not meet these criteria.
The easy way to misread this
Do not conclude that the supplement prevents skin tears or pressure injuries. The study measured forearm hydration and elasticity, no participant developed a skin tear, and the supplement contained collagen peptides, vitamins, and minerals while meals were modified.