PTOTRCTEuropean journal of physical and rehabilitation medicine2026

Effect of an ERAS-based pulmonary rehabilitation exercise program on perioperative outcomes in liver resection patients: a prospective study.

Lei Zhuang, Xuqian Yang, Ziyang Zhang and 8 others

PMID 42059670

WHAT IT FOUND

After liver resection, a nurse-led pulmonary rehabilitation bundle added to routine care improved lung function, daily activity, and walking, and reduced atelectasis and clots.

Do not credit one component alone.

Key findings

01The program added to routine care produced higher lung function values and lower Borg dyspnea values than routine care alone on days 1, 3, and 5 after surgery.

02Atelectasis occurred in 5 of 100 intervention patients and 17 of 102 control patients; deep vein thrombosis occurred in 8 of 100 and 25 of 102.

03Postoperative ADL scores, grip strength, and 6-minute walk test values were higher in the intervention group than in the control group after the intervention, while laboratory markers did not differ.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTs

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What it does not show

Assignment was by odd or even admission sequence, not by a described random number generator or concealed allocation, so the groups may not be comparable. The paper does not report blinding of patients, nurses, or outcome assessors. The intervention was a multi-component nurse-delivered bundle, so the contribution of any single exercise, educational, or monitoring part cannot be separated. Outcomes were measured only at baseline and days 1, 3, and 5, and the authors state there was no long-term follow-up. The authors state the sample size was relatively small and that some pulmonary measures, such as maximal voluntary ventilation and vital capacity percentage, were not included. Psychological outcomes, patient satisfaction, and qualitative feedback were not directly collected. The paper reports lower cost values but says no formal cost-effectiveness analysis was performed. Several table values are reported without units or scale ranges in the supplied text.

Declared interests

No conflicts of interest were declared. Funding came from Wenzhou Science and Technology Bureau and Zhejiang Provincial Natural Fund grants.

The easy way to misread this

Do not read the lung function gains as proof that one exercise component caused them. The intervention was a nurse-delivered bundle added to routine care, and assignment was by admission sequence odd or even, so the contribution of any single part cannot be separated.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →