OTNarrative ReviewFrontiers in rehabilitation sciences2025

Does prism adaptation treatment reduce spatial neglect and improve function?

Peii Chen, Kimberly Hreha, Catrina MacPhee and 2 others

PMID 39981202

WHAT IT FOUND

Prism adaptation for spatial neglect after stroke has inconsistent evidence: randomized trial reviews found no evidence of benefit on standard impairment or functional tests, while retrospective rehabilitation records reported associations with better function and more sessions.

Key findings

01Reviews of randomized trials found inconsistent evidence for prism adaptation reducing spatial neglect on common impairment or functional tests.

02Retrospective clinical records reported a three point difference in total Functional Independence Measure between matched groups that did and did not receive 8 to 12 prism adaptation sessions.

03The reviewed trials varied in prism strength, arm visibility, treatment intensity, and outcome measures, and only three met the real world efficacy stage criteria.

STILL TO COME

How it was doneWhat they foundWhat it means for OTs

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What it does not show

This is a narrative review, not a randomized trial, so it does not directly test whether prism adaptation works. The studies reviewed used different prism strengths, arm visibility, activities, session numbers, and outcome measures, so their results cannot be combined into a clear treatment recommendation. The retrospective clinical analyses are based on medical records and matched groups, so they show associations rather than proof of effect. The clinical analyses compared patients who did and did not receive prism adaptation, but patients also received regular rehabilitation. The review authors selected and categorized studies themselves, and excluded two studies from the 22 studies included in the meta-analyses, so their stage classification is their interpretation.

Declared interests

The authors declare that no financial support was received for the research, authorship, or publication.

The easy way to misread this

Do not conclude that prism adaptation alone improves spatial neglect after stroke. Reviews of randomized trials found no evidence of benefit on standard impairment or functional tests, and retrospective clinical records cannot separate prism adaptation from regular rehabilitation.

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