RNSurveyResearch in nursing & health2026

Do Injury, Depression, and PTSD Mediate the Relationships Between Latent Profiles of Cumulative Lifetime Violence and Chronic Pain Disability in Men?

Judith Wuest, Sue O'Donnell, Kelly Scott-Storey and 2 others

PMID 41388240

WHAT IT FOUND

Canadian men reporting severe lifetime violence as both targets and perpetrators had the highest chronic pain disability; PTSD and injuries were associated with pain disability, depression was not.

Key findings

01The violence profile with highest target and perpetrator severity had the highest chronic pain disability scores.

02Only the highest severity violence profile had a significant indirect effect on chronic pain disability through injuries.

03PTSD symptoms were a significant indirect pathway for Profiles 2, 3, and 4, while depression was not.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The study is cross-sectional, so it shows associations, not that violence, PTSD, or injuries caused pain disability. It did not test any treatment, so it cannot show that trauma-informed care reduces pain disability. Participants were Canadian men who reported violence experience; results may not apply to women, people without violence experience, or other countries. Data were self-reported and collected in June 2020, early in the pandemic, which may have affected stress and symptom reporting. Some missing data were imputed, and the violence profiles came from a prior analysis.

Declared interests

The authors declared no conflicts of interest. The study was funded by a New Brunswick Health Research Foundation Bridge Grant.

The easy way to misread this

Do not read these findings as proof that violence caused chronic pain or that trauma- and violence-informed care will reduce disability. The data are cross-sectional and no intervention was tested.

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