Differences in determinants affecting longitudinal change of brachial-ankle pulse wave velocity due to differences in baseline among Japanese male workers.
Atsushi Inomoto, Junko Deguchi, Rika Fukuda and 2 others
PMID 34539073WHAT IT FOUND
In Japanese male workers, determinants of worsening arterial stiffness depended on baseline risk.
Those with high baseline stiffness saw worsening linked to increasing visceral fat. Those with low baseline stiffness saw worsening linked to rising diastolic blood pressure and heart rate. Lifestyle factors showed no association.
Key findings
01Participants with high baseline brachial-ankle pulse wave velocity showed a significant relationship between worsening arterial stiffness and increasing visceral fat area.
02Participants with low baseline brachial-ankle pulse wave velocity showed a significant relationship between worsening arterial stiffness and increasing diastolic blood pressure and heart rate.
03Lifestyle factors, including smoking and physical activity, were not associated with changes in arterial stiffness in either group.
STILL TO COME
How it was doneWhat they foundWhat it means for PTs
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What it does not show
The study included only male workers, so findings do not apply to women. The sample size was small (97 participants), limiting statistical power. Metabolic syndrome risk factors were determined by self-report rather than medical examination. The explanatory power of the model for the high baPWV group was low.
Declared interests
The authors declare that they have no conflict of interest.
The easy way to misread this
Do not interpret the lack of association between lifestyle factors and arterial stiffness change as evidence that smoking or inactivity are harmless. This study looked at four-year changes in a specific worker population; baseline differences in lifestyle were present, and self-reported data may have obscured true associations.