Compressed Sensing-Based Cine-MRI for Location of Dysphagia and Swallowing Function assessment in Patients with Head and Neck Cancer: A Comparative Study.

This was a single-centre study with 36 patients and 10 controls, so the findings need confirmation in larger groups. Patients had to cooperate with MRI and swallow supine, and people with cognitive dysfunction, aphasia, other swallowing diseases, or tongue base cancer were excluded, so it does not represent many head and neck cancer patients. The study did not compare Cine-MRI with VFSS or another reference standard for clinical diagnosis, and it did not follow patients for swallowing outcomes. The Cine-MRI method had low spatial resolution and single-slice acquisition, so some structures can be blurred and the glottis may be poorly depicted. Measurement precision was limited to 74 milliseconds. Patients had different treatments, including chemotherapy, radiotherapy, or concurrent chemoradiotherapy, and tumor sites, so imaging differences cannot be assigned to one treatment or one tumor effect alone. The ROC analysis used combined parameters but did not report external validation.

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Do not conclude that compressed sensing Cine-MRI should replace VFSS or that its timing differences prove a patient will improve with targeted exercises. The study only showed group imaging differences in 36 patients and 10 controls, with no clinical outcome follow-up and no direct comparison with VFSS.