Comparison of respiratory function, physical function, and activities of daily living among community-dwelling patients with respiratory and non-respiratory disease.
Eisuke Kogure, Takeshi Ohnuma, Yuta Sugita and 1 others
PMID 35291480WHAT IT FOUND
Patients with respiratory disease had significantly shorter maximum phonation times than those without, averaging 8.9 seconds versus 13.5 seconds.
However, there were no differences in grip strength, chair stand performance, or daily living independence between the groups.
Key findings
01Maximum Phonation Time was significantly shorter in the respiratory disease group compared to the non-respiratory group.
02There were no significant differences in grip strength, 30-second chair stand test scores, Functional Independence Measure scores, or Life-space Assessment scores between the groups.
03A Maximum Phonation Time cutoff of 10.1 seconds had a positive predictive value of 31.2% and a negative predictive value of 83.5% for identifying respiratory disease.
STILL TO COME
How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs
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What it does not show
The sample size for the respiratory disease group was very small, with only 19 patients, which limits the statistical power and generalizability of the findings. The study did not account for potential confounders such as height, weight, nutritional status, or vocal cord function, which could influence MPT and physical function measures. The low prevalence of respiratory disease in the sample (16.5%) resulted in a low positive predictive value for the MPT cutoff, meaning many patients with short MPTs did not have respiratory disease. This was a cross-sectional design, so it cannot determine whether respiratory disease causes changes in MPT or if there is a causal relationship with physical function.
Declared interests
The authors declare no conflict of interest.
The easy way to misread this
Do not use the 10.1-second MPT cutoff as a definitive diagnostic tool for respiratory disease. The positive predictive value was only 31.2%, meaning that fewer than one-third of patients with an MPT below this threshold actually had respiratory disease in this sample.