Case Report: Improving gait and fatigue in multiple sclerosis through wearable electrical stimulation: a single-patient study.

This is a single-case report, so it describes what happened to one patient and cannot show that the suit works for other people with multiple sclerosis. There was no control group or sham stimulation, so practice effects, expectation, natural symptom fluctuation, or other unmeasured factors cannot be ruled out. The patient had mild-to-moderate stable disease, no recent relapses, no new lesions, and no disease-modifying or pharmacological treatment, which limits how far the result applies to more active, more disabled, or medicated patients. A single evaluator who knew the treatment timeline performed the clinical tests, which could introduce measurement bias. The paper did not include direct neurophysiological measures such as EMG or TMS, so the proposed mechanisms remain hypotheses. Follow-up was only one month after stopping, so it is unclear whether gains last longer or require maintenance sessions. For some Hunova parameters, such as CoP ellipse area or stabilization time, accepted minimal clinically important differences are not established.

The authors declared that no financial support was received for this work or its publication.

Do not conclude that the Exopulse Mollii Suit improves gait, balance, or fatigue in multiple sclerosis. This was a single case report with no control group, so the changes could reflect practice effects, expectation, natural fluctuation, or other factors.