SLPCohortMolecular autism2019

Behavioral characteristics of autism spectrum disorder in very preterm birth children.

Li-Wen Chen, Shan-Tair Wang, Lan-Wan Wang and 6 others

PMID 31367295

WHAT IT FOUND

Overall observed autism severity was similar between preterm children with autism and term children with autism.

Parent-reported social interaction showed a different pattern. Preterm children had worse nonverbal social behaviors, but better peer relationships and socioemotional reciprocity.

Key findings

01Overall autism severity by standardized clinical observation did not differ between the 18 preterm autism children and the 44 term autism children.

02Parent-reported social interaction showed a mixed pattern. Preterm autism children had more severe nonverbal social behavior problems, but better peer relationships and socioemotional reciprocity than term autism children.

03In the very preterm cohort, 19 of 246 children met autism criteria at age 5.

STILL TO COME

How it was doneWhat they foundWhat it means for SLPs

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What it does not show

The preterm autism group was small, with 18 children analyzed, so the finding needs confirmation. 1 preterm child with severe cerebral palsy and profound intellectual disability was excluded, so the result does not describe the most disabled preterm children. The examiner knew which children were born preterm, which could influence observation. Term autism children were recruited from clinics, not from the same population cohort, so the groups may differ in ways other than preterm birth. Parent interview relies on caregiver recall, and parents of preterm children may report behavior differently. Children were assessed at age 5, not earlier, so the study does not show how these patterns appear before the usual intervention window.

Declared interests

The paper reports funding from the Ministry of Science and Technology, Taiwan and National Cheng Kung University. No competing interests statement is provided in the supplied text.

The easy way to misread this

Do not read the better peer relationship and socioemotional reciprocity scores as evidence that preterm birth improves social outcomes. The clinician-observed overall severity did not differ, the preterm autism group was small, and parent report could be biased.

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