OTSLPSystematic ReviewAutism in adulthood2025

Autism and the Menopause Transition: A Mixed-Methods Systematic Review.

Aimee Grant, Harriet Axbey, Willow Holloway and 5 others

PMID 41210301

WHAT IT FOUND

Autistic people assigned female at birth described menopause as harder to understand and manage, with sensory overload, fatigue, sleep problems, thinking and memory changes, and work strain.

Online peer support helped, while healthcare often felt dismissive or unsafe.

Key findings

01Autistic people often lacked knowledge about menopause, and online peer support helped them learn about symptoms and practical strategies.

02Menopause was commonly reported to worsen fatigue, sleep, thinking and memory, and sensory sensitivity.

03Many participants described professional menopause support as negative, and access to HRT appeared limited.

STILL TO COME

How it was doneWhat they foundWhat it means for OTsWhat it means for SLPs

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What it does not show

The review included only eight peer-reviewed studies, supplemented with seven pieces of grey literature. Searches were limited to English language publications. Participants were mostly recruited online, so they may not represent all Autistic people. Most studies did not report ethnicity, and where ethnicity was reported, many participants were white. The research team did not include Autistic people with co-occurring intellectual disabilities. No included sources reported the views of people who support Autistic people during menopause. There was limited evidence on pain, incontinence, urogenital symptoms, sex life impacts, and HRT. No study evaluated an intervention, so the review cannot show whether any treatment works. Comparative data came from small samples.

The easy way to misread this

Do not read these themes as evidence that any treatment works. None of the included studies evaluated an intervention, so the paper can describe needs and experiences but cannot show whether support, HRT, or self-management helps.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →