RNCohortNursing & health sciences2025

Association Between Preoperative Frailty Using Frailty Index-Laboratory Test and Clinical Outcomes in Older Adults Undergoing Brain Tumor Surgery.

Sang Ok Kim, Youn-Jung Son, JiYeon Choi

PMID 40545253

WHAT IT FOUND

Frailty from routine blood tests and vital signs before brain tumor surgery was not linked to longer hospital stay, but it was linked to more 90-day readmissions and more non-home discharge, though only 8 patients had high frailty.

Key findings

01Moderate frailty was associated with 90-day readmission odds 1.5 times higher than low frailty (95% CI 1.01 to 1.82).

02High frailty was associated with non-home discharge odds 2.1 times higher than low frailty (95% CI 1.03 to 2.99).

03Frailty level was not significantly associated with hospital length of stay in adjusted analysis (moderate p = 0.063, high p = 0.551).

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The study was retrospective and done at one hospital, so it can show association but not cause. Only 8 patients were in the high-frailty group, so that group's results are imprecise and should not be treated as stable. Frailty was scored only from laboratory tests and vitality signs, not from a full assessment of function, mood, cognition, or social support. Patients with more than 30% missing FI-LAB items were excluded, which may limit generalizability. Laboratory and vitality values were not always recorded on the same day, which may affect frailty scores. The study did not test whether using the FI-LAB changes care or improves outcomes.

Declared interests

The authors declared no conflicts of interest. The work was funded by the National Research Foundation of Korea.

The easy way to misread this

Do not conclude that preoperative frailty screening caused readmission or non-home discharge, or that using the FI-LAB will improve outcomes. This was a retrospective association study, not a trial, and only 8 patients were in the high-frailty group.

Read it on PubMed →