PTOtherJournal of neuroengineering and rehabilitation2022

Assessing inertial measurement unit locations for freezing of gait detection and patient preference.

Johanna O'Day, Marissa Lee, Kirsten Seagers and 5 others

PMID 35152881

WHAT IT FOUND

For detecting freezing of gait in Parkinson’s disease, three sensors on the lower back and both ankles performed best; one ankle sensor performed within 3.9% of the best set.

Patients rated wrist, ankle, and lower back sensors most wearable. Small sensor study, not therapy.

Key findings

01The best freezing-of-gait detection came from three sensors placed on the lower back and both ankles, with an accuracy score of 0.83 on the study's AUROC measure.

02A single ankle sensor detected freezing of gait within 3.9% of the best three-sensor set.

03Sixteen survey participants rated wrist, ankle, and lower back sensors as the most wearable individual sensors.

STILL TO COME

How it was doneWhat they foundWhat it means for PTs

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What it does not show

Only seven people walked the sensor course, and only four wore the eleven-sensor set, so model performance may be unstable. The survey participants and walking participants were not the same people, and the survey asked them to extrapolate home wearability from clinic experience. Walking was collected in a clinic on a course, not in the home, and participants were off medication and deep brain stimulation. All participants had known freezing of gait, so results may not apply to people without freezing or with different treatment. Models were trained mainly on freezing during continuous walking, not freezing at gait initiation. The survey sample was skewed toward people who wanted to help research. The raw-data models underperformed some previously reported hand-engineered-feature models, and comparisons across the six- and eleven-sensor sets should not be treated as absolute.

Declared interests

Funded by the National Institute of Neurological Disorders and Stroke, the National Institute of Biomedical Imaging and Bioengineering, the National Science Foundation, a Stanford Bio-X Bowes Graduate Fellowship, and an Inventec Stanford Graduate Fellowship. The supplied text does not report additional author conflicts of interest.

The easy way to misread this

Do not conclude that these sensors can already monitor freezing of gait reliably at home or that wearing one ankle sensor will change therapy. The walking data came from seven people with known freezing in a clinic course, off medication and deep brain stimulation, and the survey asked 16 people to imagine 12-hour wear based on clinic experience.

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