RNCase SeriesAdvances in skin & wound care2025

Application of Negative-Pressure Wound Therapy in Patients with Wound Complications after Flap Repair for Vulvar Cancer: A Retrospective Study.

Liangzhi Qiu, Xianrong Wu, Xiu Wang

PMID 39666827

WHAT IT FOUND

16 of 17 patients completed negative-pressure wound therapy after vulvar flap repair, and all healed in 17 to 65 days.

Nurses used a two-step sandwich seal around catheters, frequent foam changes, and turning to prevent leakage.

Key findings

01The remaining 16 patients all healed in 17 to 65 days, with a mean healing time of 43.50 ± 17.93 days.

02Three patients reported procedural pain during negative-pressure wound therapy, and no bleeding or resting pain was recorded.

03Seroma or lymphorrhea was the most common wound complication, present in 9 patients, followed by wound infection in 6 patients.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The study was conducted at a single hospital and included only 17 patients, so it cannot show how widely the approach works. It was retrospective and had no control group, so wound healing cannot be separated from the surgery, stitch removal, irrigation, positioning, or other wound care. One patient halted treatment, so the healing result applies to 16 of the 17 included patients. The authors note that 35.29% of patients were not tumor-free at the pathological resection margin, and they report no long-term follow-up to confirm safety when malignancy is present. Wound complication definitions and assessment periods differed from previous studies, making comparison difficult.

Declared interests

No funding or conflict-of-interest statement is reported in the supplied text.

The easy way to misread this

Do not read this as proof that negative-pressure wound therapy alone healed the wounds. The study had no control group, and the patients also received stitch removal, irrigation, foam changes, positioning, and other wound care, so the contribution of any single component cannot be separated.

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