PTOTSLPCohortArchives of rehabilitation research and clinical translation2025

Age Is Not the Limit-Functional Outcomes and Discharge Predictors in a Neurorehabilitation Cohort of Mixed Ages.

Mauro Silva, Armin Schnider, François Herrmann and 1 others

PMID 41477072

WHAT IT FOUND

Age alone did not predict home discharge or functional improvement in this neurorehabilitation cohort.

Instead, outcomes depended on comorbidity burden, baseline function, and length of stay. Do not exclude older patients from inpatient rehabilitation based on age.

Key findings

01Chronological age was not an independent predictor of home discharge after adjusting for clinical and functional factors.

02Age was not an independent predictor of functional improvement (ΔFIM≥10 or MRFS≥0.5).

03Higher comorbidity burden (CIRS) and lower baseline functional status were significant predictors of outcomes, whereas age was not.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for SLPs

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What it does not show

Retrospective design prevents causal inference. Data came from a single institution, limiting generalizability. Key variables like cognitive status, mood severity, caregiver support, and frailty were not measured, leading to potential residual confounding. The oldest-old (≥85 years) and highly frail patients were underrepresented. Stepwise regression methods are unstable and may overfit data. Discharge destination was dichotomized (home vs institution), ignoring intermediate options like nursing homes or transfers.

Declared interests

None declared in the text.

The easy way to misread this

Do not interpret the lack of an independent age effect as proof that age is irrelevant. Older patients in the geriatric unit (NRB) had significantly worse outcomes (lower home discharge, less functional gain) than younger patients in the high-intensity unit (NRA). These disparities were driven by higher comorbidity, lower baseline function, and likely unmeasured frailty, not just age. The study suggests age itself is not the barrier, but the clinical profile often associated with advanced age is.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →