PTOTRNCase SeriesProgress in transplantation (Aliso Viejo, Calif.)2023

A Single-Center Retrospective Evaluation of Decision-Making and Factors Motivating Hand Transplant Candidates.

Kasey R Boehmer, Cassie C Kennedy, Ian G Hargraves and 10 others

PMID 37533326

WHAT IT FOUND

In eight completed hand transplant evaluations, none proceeded to transplant.

Patients often stopped because of rehabilitation time, lifelong immunosuppression, alternative options, or social and financial strain; teams stopped others for safety or incomplete follow-up.

Key findings

01All eight completed evaluations ended without pursuing transplant; five patients initiated termination.

02Patients reported ongoing pain, prosthesis disappointment, and self-image concerns, but functional limitations in daily activities were described as overshadowing identity concerns.

03Patient-led stops were attributed to rehabilitation time, lifelong immunosuppression or polypharmacy, alternative treatments, or social and financial challenges; team-led stops were attributed to incomplete follow-up, expectations better addressed by alternatives, or contraindicated immunosuppression.

STILL TO COME

How it was doneWhat they foundWhat it means for PTsWhat it means for OTsWhat it means for RNs

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What it does not show

This was a single-center chart review of nine patients, so it may not represent other hand transplant programs. Only eight completed evaluations were analysed, and one patient was still undergoing evaluation at data collection. Reasons were limited to what clinicians documented in charts, so patients' private deliberations, family discussions, and undocumented concerns may be missing. The study could not confirm whether patients sought evaluation at another transplant center. Patients who opted out of research were excluded. Because this is a qualitative case series, it describes decision patterns rather than proving that any factor causes withdrawal or regret. No structured shared decision-making process was documented, so agreement between patient and team could not be assessed.

Declared interests

The authors declared no potential conflicts of interest with the research, authorship, or publication of this article.

The easy way to misread this

Do not read the absence of transplants as evidence that hand transplant is ineffective or unsafe. This study reviewed evaluations, not transplants, and no completed evaluation led to transplant because patients withdrew or clinicians deemed them unsuitable.

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