A Randomized Controlled Trial of a Physical Activity Intervention for Self-management of Fatigue in Adolescents and Young Adults With Cancer.

The sample was small, and group comparisons by diagnosis were not possible. Three control participants withdrew after baseline, and many accelerometer records were missing, including 7 post-study records in each group. Most participants were white women with breast cancer, so results may not apply to other AYAs. The self-efficacy and self-regulation questionnaires had limited use in AYA oncology. The intervention may not have provided enough support or intensity to overcome barriers during treatment. Some participants had active disease, treatment complications, or disease progression, so increased physical activity may not have been realistic. Not every participant used the Fitbit, so the tracking component was not fully delivered for all. Participants were enrolled regardless of cancer diagnosis, prior physical activity level, or baseline fatigue severity.

The authors report no conflicts of interest. The article is listed as supported by NIH extramural research.

Do not conclude that the program improved fatigue because the intervention group showed favorable trends. The between-group comparisons were null, and none of the group-by-time interactions were statistically significant.