SLPOtherDysphagia2021

A Preliminary Investigation of Whether HRCA Signals Can Differentiate Between Swallows from Healthy People and Swallows from People with Neurodegenerative Diseases.

Cara Donohue, Yassin Khalifa, Subashan Perera and 2 others

PMID 32889627

WHAT IT FOUND

HRCA neck sensors, statistical methods, and machine learning correctly sorted 99% of thin liquid swallows from people with neurodegenerative diseases and healthy adults.

This preliminary work did not explain which swallowing problem caused the difference.

Key findings

01A set of 22 HRCA signal features helped distinguish swallows from healthy adults and swallows from people with neurodegenerative diseases.

02Logistic regression and decision tree classifiers classified swallows correctly 99% of the time, with 100% sensitivity and 99% specificity, using the full set of HRCA signal features.

STILL TO COME

How it was doneWhat they foundWhat it means for SLPs

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What it does not show

The patient group had 20 people with several different neurodegenerative diseases, so the result does not show that HRCA detects one disease or one swallowing pattern. Only thin liquid swallows were analyzed, even though the patients had been examined with a variety of bolus volumes and consistencies during clinical care. The patient VFSS data came from clinical care, while the healthy VFSS data came from a standardized research protocol, so differences between the groups may partly reflect how the data were collected. The study did not perform detailed swallow kinematic analysis beyond segmentation, so it cannot say which swallowing movement differed. This was a first preliminary study, and the authors called for larger samples, other diagnoses, other bolus textures and volumes, and future work to test diagnostic value.

Declared interests

The article is listed as supported by NIH extramural research. The supplied article text does not include a conflict of interest declaration.

The easy way to misread this

Do not read the 99% accuracy as proof that HRCA can diagnose dysphagia in your clinic. It classified swallows in a preliminary thin liquid analysis, not a clinical diagnostic test, and it did not show which swallowing physiology differed.

Read it on PubMed →