TOPIC

Neurological research

Everything we have read on neurological. Each paper is summarised from the full article rather than its abstract, so the limitations are in there too, and the funding wherever the paper declares it.

3,875 PAPERS · PAGE 53 OF 78 · NEWEST FIRST

• PTOTOther2024Effects of multidisciplinary inpatient rehabilitation on everyday life physical activity and gait in patients with multiple sclerosis.Journal of neuroengineering and rehabilitationMultidisciplinary inpatient rehabilitation improved walking capacity and self-reported mobility in people with multiple sclerosis, but these gains did not translate into faster or longer walking at home. Mildly disabled patients walked slightly more, while severely disabled patients showed no change in daily activity.
• PTOTNarrative Review2024Integration of music-based game approaches with wearable devices for hand neurorehabilitation: a narrative review.Journal of neuroengineering and rehabilitationWearable devices paired with music-based games can make hand rehabilitation more engaging and measurable. Across 16 small studies, these systems tracked finger movements and provided feedback that improved motor outcomes in stroke and spinal cord injury patients, though the evidence remains preliminary.
• PTOTRCT2024Motor imagery-based brain-computer interface rehabilitation programs enhance upper extremity performance and cortical activation in stroke patients.Journal of neuroengineering and rehabilitationAdding motor imagery brain-computer interface training to standard therapy improved upper limb function in stroke patients more than standard therapy alone. Brain scans showed increased activation in motor and visual processing areas, which correlated with the physical improvements.
• PTOTSLPOther2024A scoping review on examination approaches for identifying tactile deficits at the upper extremity in individuals with stroke.Journal of neuroengineering and rehabilitationCurrent stroke touch tests rely on subjective patient responses at rest, often missing the active exploration used in daily life. They rarely compare against healthy controls or check peripheral nerves, limiting their ability to pinpoint where sensory pathways break down.
• PTOTRCT2024Exoskeleton rehabilitation robot training for balance and lower limb function in sub-acute stroke patients: a pilot, randomized controlled trial.Journal of neuroengineering and rehabilitationAdding REX exoskeleton training to standard care improved balance scores more than standard care alone in sub-acute stroke. However, this was a small pilot study of 24 patients, so the results are preliminary and require confirmation in larger trials.
• PTOTCohort2024Cross-Frequency Coupling as a Biomarker for Early Stroke Recovery.Neurorehabilitation and neural repairEarly after stroke, brain activity shows stronger coupling between frontal and motor areas during movement. This elevated coupling linked to better motor scores and recovery, suggesting it may be a compensatory mechanism that decreases as function improves.
• PTPilot2024Evaluation of walking activity and gait to identify physical and mental fatigue in neurodegenerative and immune disorders: preliminary insights from the IDEA-FAST feasibility study.Journal of neuroengineering and rehabilitationFree-living gait from a lower-back sensor did not reliably identify self-reported physical or mental fatigue in people with neurodegenerative or immune disorders. Step count and walking time were especially poor indicators, so clinicians cannot use wearable walking summaries to infer fatigue.
• PTOTOther2024Performance of Dietary Behaviors in Chronic Community-Dwelling Stroke Survivors: A Mixed-Methods Study.Occupational therapy in health careStroke survivors rate dietary tasks as highly important but perform them less often and need assistance. Rehabilitation training on meal preparation and shopping is often insufficient. Survivors rely on adaptive equipment and strategies, though many find these underutilized or hard to access.
• PTOTCohort2024Psychosocial reintegration post-traumatic spinal cord injury in Rwanda: An exploratory study.The South African journal of physiotherapyTraumatic spinal cord injury survivors in Rwanda reported poor community reintegration. Men and those with paraplegia fared better than women and those with tetraplegia. These findings highlight the need for rehabilitation services that address gender-specific barriers and support those with higher-level injuries.
• PTOTCohort2024Factors associated with independent ambulation at 3 months after putaminal hemorrhage: an observational study.Journal of physical therapy scienceThree months after putaminal hemorrhage, hip movement ability, cognitive score, and ventricular rupture predicted independent walking. A hemiplegia grade of 6 or higher was the strongest predictor, with 100% specificity for ambulation.
• PTPilot2024A backward cycling programme for people with Parkinson's disease: a feasibility and preliminary results study.Journal of rehabilitation medicineTwenty-two people with mild to moderate Parkinson's disease completed a six-week backward cycling programme. They showed improvements in backward stepping responses, gait velocity, and balance. However, the study lacked a control group, so these changes cannot be definitively attributed to the intervention.
• PTCase Series2024Time synchronization between parietal-frontocentral connectivity with MRCP and gait in post-stroke bipedal tasks.Journal of neuroengineering and rehabilitationIn ten post-stroke patients, brain connectivity measured by EEG changed around voluntary knee movement and could classify left or right foot intent with 75.1% accuracy in a 200 ms window before movement started.
• PTOther2024Post-stroke hand gesture recognition via one-shot transfer learning using prototypical networks.Journal of neuroengineering and rehabilitationAdapting a hand-gesture model to a new stroke survivor with one sample identified 82.20% of seven gestures correctly, similar to models trained on that person's own data.
• PTOther2024Mapping of spastic muscle activity after stroke: difference between passive stretch and active contraction.Journal of neuroengineering and rehabilitationIn people with post-stroke spasticity, the brain's stretch response and voluntary muscle use happen in different parts of the biceps. Passive stretch activated areas further down the muscle, while voluntary contraction focused on the top, with little overlap between the two.
• PTOTOther2024Automatic gait events detection with inertial measurement units: healthy subjects and moderate to severe impaired patients.Journal of neuroengineering and rehabilitationAn algorithm using foot-worn sensors accurately detected gait events in healthy people and in patients with multiple sclerosis or post-stroke foot deformity. It matched the gold standard without needing extra equipment, offering a practical tool for clinical gait analysis.
• PTRCT2024Distinct effects of long-term Tai Chi Chuan and aerobic exercise interventions on motor and neurocognitive performance in early-stage Parkinson's disease: a randomized controlled trial.European journal of physical and rehabilitation medicineBoth 12-week aerobic exercise and Tai Chi improved Parkinson's motor symptoms. Only aerobic exercise improved reaction time; Tai Chi did not. Accuracy did not improve. Control participants worsened.
• PTOTSLPCohort2024Survival and predictive factors of clinical outcome in patients with severe acquired brain injury.European journal of physical and rehabilitation medicinePatients with severe brain injury who had tracheostomies survived as long as those without, but remained heavily disabled. Younger age predicted better survival and walking ability, yet most patients could not walk or eat by mouth after discharge.
• PTCohort2024Post-stroke spasticity: follow-up and functional implications of chronic long-term treatment with botulinum toxin.European journal of physical and rehabilitation medicineOver four years, 36 chronic stroke survivors receiving botulinum toxin and rehabilitation showed stable improvements in balance and fall risk (TUG). However, gains in walking endurance and speed declined over time, with fewer patients reaching clinically meaningful thresholds in later cycles.
• PTOTSurvey2024Orthotist involvement in early gait rehabilitation after stroke: A cross-sectional survey of orthotists in the United Kingdom.Prosthetics and orthotics internationalMost orthotists felt they should be routinely involved in early stroke gait rehabilitation without a specific referral, but only 5% reported being involved that way. They were confident in prescribing ankle-foot orthoses but less confident advising on broader therapy.
• PTPilot2024The relationship between sleep quality and gait in people with multiple sclerosis: A pilot study.Hong Kong physiotherapy journal : official publication of the Hong Kong Physiotherapy Association Limited = Wu li chih liaoIn 41 adults with MS, poorer sleep was linked to gait. Lower sleep efficiency related to shorter steps, and more awakenings related to slower walking and shorter step time.
• PTOTSLPOther2024Co-design of a walking activity intervention for stroke survivors.Frontiers in rehabilitation sciencesStroke survivors rarely walk just for exercise. They need walking linked to valued social goals, supported by objective step feedback and carer involvement. A new co-design toolbox provides these elements, but efficacy is untested.
• PTOTSurvey2024Needs Assessment of Self-Management for Individuals With Chronic Spinal Cord Injury/Disease.OTJR : occupation, participation and healthPeople with chronic spinal cord injury ranked virtual meetings and group discussions as the most important features for a self-management program. Psychological health and coping were rated the top content priority, far ahead of respiratory or autonomic issues.
• PTOTCase-Control2024Robot-aided assessment and associated brain lesions of impaired ankle proprioception in chronic stroke.Journal of neuroengineering and rehabilitationMost adults with chronic stroke showed impaired ankle position and motion sense on robotic testing. These deficits were linked to lesions in the insula and temporoparietal regions. Standard clinical scales may miss these subtle proprioceptive losses that affect balance.
• PTOTSLPQualitative2024Experiences of chain of care and rehabilitation after stroke: a qualitative study of persons discharged to skilled nursing facilities before returning home.Journal of rehabilitation medicineStroke survivors discharged to skilled nursing facilities reported lacking information on fatigue and prevention, and felt excluded from rehabilitation planning. They valued immediate provision of aids upon returning home, but faced delays in mobility services and inconsistent training support.
• PTSystematic Review2024Bicycling for Rehabilitation of Persons With Parkinson Disease: A Scoping Review.Journal of neurologic physical therapy : JNPTStationary bicycling reduces Parkinson's disease severity and improves walking speed. These changes were clinically meaningful, especially with speed-focused training. Balance scores improved but did not reach a level considered meaningful for patients.
• PTOTSLPCohort2024Utilization and features of rehabilitation and health services for persons with spinal cord injury.European journal of physical and rehabilitation medicineIn Swiss spinal cord injury rehab, nursing, physiotherapy and occupational therapy take the most time. Patients with higher cervical injuries and lower function receive far more services per day, while those with better function receive fewer.
• PTRCT2024Training effect of repeated rolling motions on boccia players with severe cerebral palsy: comparison with the effect of conventional upper-limb training using a crossover test.Journal of physical therapy scienceRepeated side-to-side rolling for 4 weeks improved throwing distance and shoulder and hip motion in seated boccia players with severe cerebral palsy. Upper-limb band training did not improve throwing distance.
• PTOTCohort2024Perceived and physiological strains of societal participation in people with multiple sclerosis: a real-time assessment study.Journal of rehabilitation medicineFor people with MS, how strenuous an activity feels does not predict how hard their heart works. Perceived strain was linked to fatigue, not physiology. Clinicians should treat fatigue and perceived effort directly, rather than assuming physical exertion drives the complaint.
• PTOTOther2024Trend change analysis of postural balance in Parkinson's disease discriminates between medication state.Journal of neuroengineering and rehabilitationTrend change analysis detected differences between medication states in Parkinson's disease that standard sway measures missed. However, neither method distinguished patients from healthy controls during quiet standing.
• PTCase Series2024Wearable biofeedback device to assess gait features and improve gait pattern in people with parkinson's disease: a case series.Journal of neuroengineering and rehabilitationWalking speed and distance improved after three days of waist vibration feedback in seven men with Parkinson's disease, but no control group means the device was not shown to cause the change.
• PTOTSLPCohort2024Comparison of motion sensor and heart rate monitor for assessment of physical activity intensity in stroke outpatient rehabilitation sessions: an observational study.Journal of rehabilitation medicineMotion sensors and heart rate monitors give very different readings of how hard stroke patients work in rehab. One device showed no moderate activity while the other showed plenty. Do not rely on a single device to judge session intensity.
• PTOTSLPRCT2024Effect of repetitive peripheral magnetic stimulation of the common fibular nerve on the soleus muscle Hoffmann reflex.Journal of physical therapy scienceRepetitive magnetic stimulation of the common fibular nerve reduced soleus muscle H-reflex amplitude in healthy men, suggesting increased spinal inhibition. However, the control group also showed changes, and the clinical effect on spasticity or function in patients was not tested.
• PTOTSLPCase Report2024Implementing neuropsychological rehabilitation following severe traumatic brain injury in a low-to-middle income country: a case report.Frontiers in rehabilitation sciencesA man with severe brain injury used iPad checklists and loud calendar alerts to regain daily independence, but standard cognitive tests showed no improvement. Family reported better task completion and reduced conflict, while the patient’s physical function actually worsened. This single case cannot prove the method works.
• PTOTOther2024Validity and reliability of the chronic composite XA, an upper limb motor assessment using Active Range of Motion in patients with chronic stroke.European journal of physical and rehabilitation medicineIn 28 chronic stroke patients, a quick arm movement score against resistance tracked standard arm tests and stayed stable on retesting. Adding shoulder and forearm measurements improved the score. A gain above 64 degrees was needed to call change real.
• PTOTSLPCohort2024Stroke survivors' long-term participation in paid employment.Work (Reading, Mass.)Half of stroke survivors with pre-stroke jobs still had employment contracts at 30 months, but many were on sick leave. Those who stayed in the workforce reported better quality of life and communication, yet non-work participation remained restricted and less satisfying.
• PTOTSurvey2024Patient-reported outcome survey of user-experiences in the spinal cord injured-community with MPPT for treating wounds and pressure injuries and for controlling soft tissue infection caused by osteomyelitis.Frontiers in rehabilitation sciencesSpinal cord injury patients reported a 100% closure rate for wounds and control of fistula symptoms using MPPT powder. Most treated themselves without nursing support. These are self-reported experiences from a small group, not proof of efficacy.
• PTOTOther2024Use of cortical hemodynamic responses in digital therapeutics for upper limb rehabilitation in patients with stroke.Journal of neuroengineering and rehabilitationAdding brain activation data to digital rehab scores improved the accuracy of classifying stroke patients' motor impairment severity. Patients with limited function showed increased brain activity in motor and planning areas, while those with better function showed no significant activation.
• PTOther2024Evaluation of the accuracy of ChatGPT's responses to and references for clinical questions in physical therapy.Journal of physical therapy scienceOverall, ChatGPT's answer content was rated almost correct, but 40.5% of references were fictitious. Check every reference before using it.
• PTOTCase-Control2024Inter-joint coordination with and without dopaminergic medication in Parkinson's disease: a case-control study.Journal of neuroengineering and rehabilitationPeople with Parkinson's disease showed reduced knee movement and delayed hip flexion during walking, particularly at preferred speeds. Dopaminergic medication improved hip kinematics only at preferred speed and did not resolve these coordination deficits. Walking faster than usual may improve gait regularity.
• PTOTSystematic Review2023Effectiveness of Robotics in Stroke Rehabilitation to Accelerate Upper Extremity Function: Systematic Review.Occupational therapy internationalRobot-assisted therapy did not significantly speed up overall upper limb recovery compared to conventional therapy alone. However, gains were faster in the first 25 hours, suggesting robots may help early in rehabilitation before progress plateaus.
• PTRCT2024Submaximal, Low-Dose Eccentric vs Traditional Cycling Exercise: Reduced Oxygen Uptake and Pulmonary Artery Pressure Assessed by Echocardiography in Healthy Middle-aged Adults. A Randomized Controlled, Crossover Trial.Archives of rehabilitation research and clinical translationEccentric cycling lowered oxygen uptake by 40% and pulmonary artery pressure by 26% compared to traditional cycling in healthy adults. Participants felt less breathless but reported similar leg fatigue, suggesting a lower cardiopulmonary load at the same external work.
• PTOTSurvey2024An International and Multidisciplinary Consensus on the Labeling of Spatial Neglect Using a Modified Delphi Method.Archives of rehabilitation research and clinical translationExperts reached consensus on 'spatial neglect' as the preferred label, because 'unilateral' implies one-sided deficits while impairment follows a gradient. Use it when communicating the diagnosis.
• PTOTMeta-Analysis2024Are Middle- or Older-Aged Adults With a Spinal Cord Injury Engaging in Leisure-Time Physical Activity? A Systematic Review and Meta-Analysis.Archives of rehabilitation research and clinical translationLeisure activity in adults over 45 with spinal cord injury varies wildly. While the average moderate-to-heavy activity was 173 minutes per week, between 27% and 64% of participants reported doing none at all. This gap means you cannot assume your patients are active enough to protect their heart health.
• PTOTPilot2024Adapting the Multiple Sclerosis Functional Composite for Telehealth Administration Using Videoconference Delivery: Methodological Considerations and Interrater Reliability.Archives of rehabilitation research and clinical translationTwo raters agreed on scores from the tele-MSFC, participants accepted it, and no adverse events occurred in 61 adults with MS. It is not ready as a trial endpoint.
• PTOther2024The psychometric properties of the modified fear of falling avoidance behavior questionnaire in Parkinson's disease and older adults.Archives of physiotherapyThe modified fear-of-falling avoidance questionnaire produced consistent scores when repeated about a week apart and related to balance, mood, and step counts. It may help therapists screen avoidance behavior, not prove it predicts future falls.
• PTOTCohort2024Factors influencing the prognosis of patients with acute cerebral infarction who received usual care: a multicenter prospective cohort study.Journal of physical therapy scienceIn patients with acute cerebral infarction receiving usual care, poor functional outcome was predicted by higher initial stroke severity (NIHSS >4) and reinfarction, not by the timing of first mobilization. Age and rehabilitation intensity were not independent predictors.
• PTOTQualitative2024Rehabilitation Professionals' Perspectives on Human Rights, Disability, and Science: A Qualitative Study.Archives of rehabilitation research and clinical translationMost rehabilitation professionals for spinal cord injury did not know UN human rights conventions, though all knew the Americans with Disabilities Act. They saw barriers like equipment denial and transport as policy issues, not rights violations, yet were open to learning how to frame them as rights.
• PTOTSLPOther2024Machine learning for automating subjective clinical assessment of gait impairment in people with acquired brain injury - a comparison of an image extraction and classification system to expert scoring.Journal of neuroengineering and rehabilitationA computer model scored arm movement abnormality during walking as consistently as three experienced physiotherapists. It correctly identified impaired versus unimpaired movement in 84% of cases, matching human judgment without the usual disagreement between different clinicians.
• PTOTQualitative2024Technology Use for Home-Based Stroke Rehabilitation in Switzerland From the Perspectives of Persons Living With Stroke, Informal Caregivers, and Therapists: Qualitative Interview and Focus Group Study.JMIR rehabilitation and assistive technologiesStroke survivors and therapists in Switzerland want home technology but lack clear guidance on which tools to use. Reimbursement uncertainty and a heavy burden on informal caregivers hinder adoption, with survivors relying on therapists to filter options.
• PTPilot2024Implementation of a unilateral hip flexion exosuit to aid paretic limb advancement during inpatient gait retraining for individuals post-stroke: a feasibility study.Journal of neuroengineering and rehabilitationPhysical therapists successfully used a hip exosuit to replace manual limb assistance for severely impaired stroke patients. While it eliminated the need for hands-on limb support and increased walking distance in this group, speed changes were variable. The device did not improve outcomes for those already walking independently.