RNCohortJournal of the American Medical Directors Association2020

Trends in Antipsychotic and Mood Stabilizer Prescribing in Long-Term Care in the U.S.: 2011-2014.

Lauren B Gerlach, Helen C Kales, Hyungjin Myra Kim and 4 others

PMID 32693995

WHAT IT FOUND

After the CMS dementia-care push, antipsychotic prescribing in U.S. nursing homes fell, especially in dementia.

Mood stabilizer prescribing rose, mostly gabapentin. Adjusted antipsychotic use did not fall among residents with depression or bipolar disorder without dementia.

Key findings

01The adjusted probability of antipsychotic treatment fell from 0.120 to 0.100 overall, and fell more sharply in residents with dementia, from 0.174 to 0.136.

02Mood stabilizer treatment rose from 0.140 to 0.185 adjusted overall, and gabapentin use rose from 0.086 to 0.126.

03Among residents with depression or bipolar disorder but no dementia, adjusted antipsychotic use rose from 0.081 to 0.087, and mood stabilizer use rose from 0.193 to 0.251.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

The sample was built from Medicare claims, not nursing home assessments, and included only residents with continuous Medicare fee-for-service and Part D coverage, so it misses Medicare Advantage beneficiaries and prescriptions outside Part D. Residents with schizophrenia, Tourette’s syndrome, and Huntington’s disease were excluded from the primary analysis, so it does not describe prescribing in those groups. Claims show fills, not whether residents actually took the medication, and they do not show why it was prescribed, such as for dementia behavior, depression, bipolar disorder, or pain. The study did not capture non-drug strategies or physical restraint use, so it cannot show what else changed alongside medication trends. The analysis ends in 2014 and does not include later prescribing trends.

Declared interests

The authors declared no conflicts of interest. The article’s publication types list NIH extramural and non-U.S. government research support.

The easy way to misread this

Do not read the fall in antipsychotic prescribing as proof that prescribing became more appropriate. Mood stabilizer use rose, especially gabapentin, and the data lack prescribing indication and actual medication use.

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