The Utility of Using the All of Us Research Program to Examine AHA's Life's Essential 8.
Mary Roberts Davis, Alicia J Johnson, Quin E Denfeld and 2 others
PMID 40996158WHAT IT FOUND
All of Us data lacked diet, sleep, and physical activity, so it could not fully measure AHA's Life's Essential 8.
Only 56,565 of 399,110 adults had complete data on the five available cardiovascular indicators.
Key findings
01Diet quality, sleep duration, and physical activity were unavailable, so analyses used only blood pressure, body mass index, glucose, cholesterol, and nicotine exposure.
02399,110 adults had at least one available cardiovascular indicator, but only 56,565 had complete data for all five indicators.
03Average systolic blood pressure and BMI exceeded recommended thresholds, and median HbA1c was in the prediabetes range for males and borderline for females.
STILL TO COME
How it was doneWhat they foundWhat it means for RNs
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What it does not show
Diet quality, sleep duration, and physical activity were not available, so the study could not describe these parts of cardiovascular health. Only 56,565 of 399,110 participants had complete data for all five available indicators. Non-HDL cholesterol data were missing for approximately 50% of participants. The wearable device subset was small, with 1,790 participants, and it was younger and predominantly White. The study used existing records and enrollment-related data, not a tested intervention or patient outcome. The authors note that missing data may relate to the types of care participants received, but that was not measured directly.
Declared interests
The supplied article text does not report author conflicts or funding details; the publication types list NIH extramural research support.
The easy way to misread this
Do not conclude that AHA's Life's Essential 8 can be fully measured using this All of Us dataset. Diet, sleep, and physical activity were unavailable, and only 56,565 of 399,110 adults had complete data for the five available indicators.