QualitativeChild: care, health and development2025

The Psychological Experience of Caregivers of Children With Neuroblastoma Undergoing Naxitamab Treatment: A Qualitative Study in China.

Yan Xuan, Ziling Ji, Xiaohua Li and 5 others

PMID 40740159

WHAT IT FOUND

Caregivers of children with neuroblastoma described shock and financial ruin after diagnosis, followed by anxiety about new treatments.

Over time, they shifted focus from academic achievement to simply having a healthy child, finding hope in access to novel therapies.

Key findings

01Diagnosis was often delayed due to non-specific symptoms like fever or leg pain being misdiagnosed as common infections.

02Families faced severe financial strain, often selling assets or taking on debt to afford treatment.

03Post-treatment, caregivers reported a shift in values, prioritizing their child's survival and happiness over academic success.

STILL TO COME

How it was doneWhat they found

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What it does not show

The study was conducted at a single specialized center in China, limiting generalizability to other healthcare systems. The sample was highly educated (85.7% held a bachelor's degree or higher) and largely high-income, which may not reflect the experiences of families with fewer resources. Data collection relied on retrospective recall, which can introduce bias regarding past emotional states and events.

Declared interests

The authors declared no conflicts of interest. The study was funded by several Chinese government and medical academy grants.

The easy way to misread this

Do not interpret the caregivers' reports of hope and improved outlook as evidence that naxitamab is effective or superior to other treatments. These are subjective psychological experiences, not clinical outcomes.

Summarised by AI from the full paper, without a clinician reviewing it. Check it against the source before it changes what you do. Read it on PubMed →


The study

Participants
14 caregivers
Certainty of evidence
Very low

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    Cite

    Yan Xuan, Ziling Ji, Xiaohua Li, et al. The Psychological Experience of Caregivers of Children With Neuroblastoma Undergoing Naxitamab Treatment: A Qualitative Study in China. Child: care, health and development. 2025.

    Read the original — we summarise, we never replace the paper.