PTNarrative ReviewMusculoskeletal science & practice2025

The Neuroplastic Outcomes from Impaired Sensory Expectations (NOISE) hypothesis: How ACL dysfunction impacts sensory perception and knee stability.

Amber J Schnittjer, Janet E Simon, Tyler T Whittier, Dustin R Grooms

PMID 39586196

WHAT IT FOUND

This paper proposes a theory that ACL injuries cause long-term instability by disrupting how the brain predicts sensory feedback.

It reviews other studies to support this idea but reports no original patient data or treatment results.

What this paper is

This paper is a theoretical hypothesis proposing the 'NOISE' model for ACL injury outcomes. It reviews existing literature to argue that sensory prediction errors drive motor control deficits, but it reports no original patient data, methods, or outcomes from a trial. There are no findings here to change clinical practice on.

Read it on PubMed →