RNCohortEuropean journal of oncology nursing : the official journal of European Oncology Nursing Society2026

The impact of social determinants of health on mental and behavioral health trajectories of breast cancer survivors: A longitudinal cohort study.

Oscar Y Franco-Rocha, Jaime Fuentes-Balderrama, Bora Sun and 6 others

PMID 41319526

WHAT IT FOUND

Anxiety rose over time in 64 breast cancer survivors.

Higher financial toxicity tracked with worse reported cognitive function and fatigue, and less recreational access with more anxiety. Sleep did not change. These links were associations, not proof that interventions work.

Key findings

01Anxiety symptoms increased over time, and survivors who reported less access to recreational activities had higher overall anxiety.

02Higher financial toxicity was linked with poorer reported cognitive function and greater fatigue overall, but not with faster decline or worsening over time.

03Sleep disturbance showed no significant association with time, clinical, demographic, or social determinant variables.

STILL TO COME

How it was doneWhat they foundWhat it means for RNs

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What it does not show

Only 64 women were analysed, and there were only three timepoints, so the study may have missed small effects. Social determinant factors were measured only at the eight-month visit, so the study could not track how they changed over time. The sample was mostly non-Hispanic White, employed, partnered, highly educated, and had household income above $50,000, so findings may not apply to survivors with fewer resources. Participants were post-treatment survivors, not people currently receiving treatment, so it does not address symptom changes during active therapy. Missing data were filled with a simple imputation method, which can underestimate uncertainty. All outcomes and exposures were self-reported, and the study was observational, so it cannot prove cause.

The easy way to misread this

Do not conclude that reducing financial toxicity or improving recreational access will lower anxiety, fatigue, or cognitive complaints. The study was observational, social factors were measured only at the eight-month visit, and the associations did not show that changing them changes symptoms.

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